This chapter introduces the book and its inspiration, mission, central research questions and structure. It links the effectiveness of corporate social responsibility (CSR) to better understanding of its interdependent relationship with law, regulation and governance. The chapter shows that the book is unconstrained by conventional understandings and the neo-liberal voluntarism orthodoxy of some disciplines in suggesting opportunities for tackling substantive and procedural barriers for CSR in public international law, private international law and national law. It underlines the need for contextualism and a spectrum for possible legal and regulatory intermediation in fifteen ingredients of CSR.