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Chapter 17 - Transolfactory Spread in the Pathogenesis of Meningoencephalitis

Published online by Cambridge University Press:  27 July 2023

Robert Laureno
Robert Laureno
Affiliation:
Georgetown University, Washington DC
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Summary

Various infectious agents invade brain and spinal fluid through the olfactory nerves and bulbs. The best example is the amoeba Naegleria which usually enters the nose during recreation in fresh water. Strong epidemiologic, pathologic, and experimental evidence support this transolfactory route of neurologic infection. Viruses can also cause meningioencephalitis via transolfactory spread.

Keywords

Amoebic meningoencephalitisNaeglenia fowleriTransolfactory spreadHerpes simplex encephalitisRabies encephalitis
Type
Chapter
Information
Insights into Clinical Neurology , pp. 85 - 88
Publisher: Cambridge University Press
Print publication year: 2023

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