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Chapter 9 - What to Do If Drugs Don't Work?

Published online by Cambridge University Press:  22 May 2018

Dieter Schmidt ,
William O. Tatum  and
Steven Schachter
By
Dieter Schmidt
Dieter Schmidt
Affiliation:
Epilepsy Research Group, Free University of Berlin
William O. Tatum
Affiliation:
Department of Neurology, Beth Israel Deaconess Medical Center, Boston
Steven Schachter
Affiliation:
Department of Neurology, Beth Israel Deaconess Medical Center, Boston
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Common Pitfalls in Epilepsy
Case-Based Learning
 , pp. 156 - 170
Publisher: Cambridge University Press
Print publication year: 2018

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References

Elger, C. E., Schmidt, D. Modern management of epilepsy: a practical approach. Epilepsy Behav 2008;12(4): 501–39.CrossRefGoogle ScholarPubMed
Engel, J. Jr., Wiebe, S., French, J., et al. Practice parameter: temporal lobe and localized neocortical resections for epilepsy: Report of the Quality Standards Subcommittee of the American Academy of Neurology, in Association with the American Epilepsy Society and the American Association of Neurological Surgeons. Neurology 2003;60(4): 538–47.CrossRefGoogle Scholar
Hanley, J. A., Lippman-Hand, A. If nothing goes wrong, is everything alright? JAMA 1983;259: 1743–5.Google Scholar
Hauser, W. A. The natural history of drug resistant epilepsy: epidemiological considerations. In: Surgical treatment of epilepsy. Epilepsy Res 1992;(Suppl. 5): 25–8.Google Scholar
Kelley, K., Theodore, W. H. Prognosis 30 years after temporal lobectomy. Neurology 2005;64(11): 1974–6.CrossRefGoogle ScholarPubMed
Kossoff, E. H. More fat and fewer seizures: dietary therapies for epilepsy. Lancet Neurol 2004;3: 415–20.CrossRefGoogle ScholarPubMed
Kwan, P., Arzimanoglou, A., Berg, A. T. et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia 2010;51(6): 1069–77.CrossRefGoogle Scholar
Kwan, P., Brodie, M. J. Early identification of refractory epilepsy. New Engl J Med 2000;342: 314–39.CrossRefGoogle ScholarPubMed
Lee, P. R., Kossoff, E. H. Dietary treatments for epilepsy: management guidelines for the general practitioner. Epilepsy Behav 2011 Jun; 21(2): 115–21.Google Scholar
Löscher, W., Schmidt, D. Modern antiepileptic drug development has failed to deliver: ways out of the current dilemma. Epilepsia 2011;52(4): 657–78.CrossRefGoogle ScholarPubMed
Luciano, A. L., Shorvon, S. D. Results of treatment changes in patients with apparently drug-resistant chronic epilepsy. Ann Neurol 2007;62(4): 375–81.Google Scholar
d' Orio, P., Pelliccia, V., Gozzo, F., et al. Epilepsy surgery in patients older than 50 years: Effectiveness, safety, and predictors of outcome. Seizure 2017;50: 60–6.Google ScholarPubMed
Rathore, C., Samhita Panda, P., Sankara, S., Radhakrishnan, K. How safe is it to withdraw antiepileptic drugs following successful surgery for mesial temporal lobe epilepsy? Epilepsia 2011;52(3): 627–35.CrossRefGoogle ScholarPubMed
Schmidt, D., Baumgartner, C., Löscher, W. Seizure recurrence after planned discontinuation of antiepileptic drugs in seizure-free patients after epilepsy surgery: a review of current clinical experience. Epilepsia 2004;45: 179–86.Google Scholar
Schmidt, D., Löscher, W. How effective is surgery to cure seizures in drug-resistant temporal lobe epilepsy? Epilepsy Res 2003;56(2–3): 85–91.Google Scholar
Sillanpää, M., Schmidt, D. Natural history of treated childhood-onset epilepsy: prospective, long-term population-based study. Brain 2006;129(Pt 3): 617–24.Google Scholar
Sprengers, M., Vonck, K., Carrette, E., Marson, A. G., Boon, P. Deep brain and cortical stimulation for epilepsy. Cochrane Database Syst Rev 2017 Jul 18; 7: CD008497. doi: 10.1002/14651858.CD008497.pub3.Google ScholarPubMed
Theodore, W. H., Fisher, R. S. Brain stimulation for epilepsy. Lancet Neurol 2004;3: 111–8.CrossRefGoogle ScholarPubMed
Wiebe, S., Blume, W. T., Girvin, J. P., et al. A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med 2001;345: 311–8.Google Scholar

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