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Combination of phytase and organic acid for broilers: role in mineral digestibility and phytic acid degradation

Published online by Cambridge University Press:  19 October 2018

B.S. VIEIRA Open the ORCID record for B.S. VIEIRA [Opens in a new window] ,
J.G. CARAMORI JUNIOR ,
C.F.S. OLIVEIRA  and
G.S.S. CORREA
B.S. VIEIRA*
Affiliation:
College of Veterinary Medicine, Federal University of Mato Grosso. 2367 Fernando Correa da Costa Avenue, Cuiaba-MT-Brazil, 78060-900
J.G. CARAMORI JUNIOR
Affiliation:
College of Veterinary Medicine, Federal University of Mato Grosso. 2367 Fernando Correa da Costa Avenue, Cuiaba-MT-Brazil, 78060-900
C.F.S. OLIVEIRA
Affiliation:
College of Veterinary Medicine, Federal University of Mato Grosso. 2367 Fernando Correa da Costa Avenue, Cuiaba-MT-Brazil, 78060-900
G.S.S. CORREA
Affiliation:
College of Veterinary Medicine, Federal University of Mato Grosso. 2367 Fernando Correa da Costa Avenue, Cuiaba-MT-Brazil, 78060-900
*
Corresponding author: vieirabs@hotmail.com
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Abstract

The following review covers current and classical knowledge regarding the positive effects of organic acids on phytase activity and phytate P availability in broiler chickens. Despite the improvements achieved for phytase stability under gastrointestinal conditions, intrinsic characteristics of phytic acid, dietary components and the digestive tract favour phytate formation and, consequently, inhibit the degradation of phytic acid and other inositol phosphates by phytase. Organic acids, more frequently citric acid, have been shown to decrease phytate establishment and enhance phytase activity. When supplemented alone, citric acid increased P retention by 16 to 34% and phytate P retention by 105% in broilers. When combined with phytase, 3.27% better tibia ash has been reported. From the available data, it appears that combined use of phytases and organic acids deserves greater consideration in modern poultry nutrition.

Keywords

chelatorfeed acidificationfeed enzymepHphosphorusphytate
Type
Review
Information
World's Poultry Science Journal , Volume 74 , Issue 4 , December 2018 , pp. 711 - 726
Copyright
Copyright © World's Poultry Science Association 2018 

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References

AFSHARMANESH, M. and POURREZA, J. (2005) Effects of calcium, citric acid, ascorbic acid, vitamin d3 on the efficacy of microbial phytase in broiler starters fed wheat-based diets. I. performance, bone mineralisation and ileal digestibility. International Journal of Poultry Science 4: 418-424.Google Scholar
AKYUREK, H., OZDUVEN, M.L., OKUR, A.A., KOC, F. and SAMLI, H.E. (2011) The effects of supplementing an organic acid blend and/or microbial phytase to a corn-soybean based diet fed to broiler chickens. African Journal of Agricultural Research 6: 642-649.Google Scholar
BIGGS, P. and PARSONS, C.M. (2008) The effects of several organic acids on growth performance, nutrient digestibilities, and cecal microbial populations in young chicks. Poultry Science 87: 2581-2589.Google Scholar
BOLING, S.D., WEBEL, D.M., MAVROMICHALIS, I., PARSONS, C.M. and BAKER, D.H. (2000) The effects of citric acid on phytate-phosphorus utilisation in young chicks and pigs. Journal of Animal Science 78: 682-689.Google Scholar
BOLING-FRANKENBACH, S.D., SNOW, J.L., PARSONS, C.M. and BAKER, D.H. (2001) The effect of citric acid on the calcium and phosphorus requirements of chicks fed corn-soybean meal diets. Poultry Science 80: 783-788.Google Scholar
BRENES, A., VIVEROS, A., ARIJA, I., CENTENO, C., PIZARRO, M. and BRAVO, C. (2003) The effect of citric acid and microbial phytase on mineral utilisation in broiler chicks. Animal Feed Science and Technology 110: 201-219.Google Scholar
CENTENO, C., ARIJA, I., VIVEROS, A. and BRENES, A. (2007) Effects of citric acid and microbial phytase on amino acid digestibility in broiler chickens. British Poultry Science 48: 469-479.Google Scholar
CHERYAN, M. and RACKIS, J.J. (1980) Phytic acid interactions in food systems. C R C Critical Reviews in Food Science and Nutrition 13: 297-335.Google Scholar
CHOWDHURY, R., ISLAM, K.M.S., KHAN, M.J., KARIM, M.R., HAQUE, M.N., KHATUN, M. and PESTI, G.M. (2009) Effect of citric acid, avilamycin, and their combination on the performance, tibia ash, and immune status of broilers. Poultry Science 88: 1616-1622.Google Scholar
COWIESON, A.J., RUCKEBUSCH, J.P., KNAP, I., GUGGENBUHL, P. and FRU-NJI, F. (2016) Phytate-free nutrition: a new paradigm in monogastric animal production. Animal Feed Science and Technology 222: 180-189.Google Scholar
DEMIREL, G., PEKEL, A.Y., ALP, M. and KOCABAGLI, N. (2012) Effects of dietary supplementation of citric acid, copper, and microbial phytase on growth performance and mineral retention in broiler chickens fed a low available phosphorus diet. Journal of Applied Poultry Research 21: 335-347.Google Scholar
DENBOW, D.M. (2015) Gastrointestinal anatomy and physiology, Sturkie's Avian Physiology, pp. 337-366. Sixth edition. (Elsevier).Google Scholar
DERSJANT-LI, Y., AWATI, A., SCHULZE, H. and PARTRIDGE, G. (2015) Phytase in non-ruminant animal nutrition: a critical review on phytase activities in the gastrointestinal tract and influencing factors. Journal of the Science of Food and Agriculture 95: 878-896.Google Scholar
DESHPANDE, S.S. and CHERYAN, M. (1984) Effects of phytic acid, divalent cations, and their interactions on α-amylase activity. Journal of Food Science 49: 516-519.Google Scholar
EBRAHIMNEZHAD, Y., SHIVAZAD, M., TAHERKHANI, R. and NAZERADL, K. (2008) Effects of citric acid and microbial phytase supplementation on performance and phytate phosphorus utilisation in broiler chicks. The Journal of Poultry Science 45: 20-24.Google Scholar
EISENBERG, F. and PARTHASARATHY, R. (1987) Measurement of biosynthesis of myo-inositol from glucose 6-phosphate, Methods in Enzymology, Vol. 141, pp. 127-143 (Academic Press).Google Scholar
EMAMI, N.K., NAEINI, S.Z. and RUIZ-FERIA, C.A. (2013) Growth performance, digestibility, immune response and intestinal morphology of male broilers fed phosphorus deficient diets supplemented with microbial phytase and organic acids. Livestock Science 157: 506-513.Google Scholar
EMSLEY, J. and NIAZI, S. (1981) The structure of myo-inositol hexaphosphate in solution: 31P N.M.R. investigation. Phosphorus and Sulfur and the Related Elements 10: 401-407.Google Scholar
ESMAEILIPOUR, O., SHIVAZAD, M., MORAVEJ, H., AMINZADEH, S., REZAIAN, M. and VAN KRIMPEN, M.M. (2011) Effects of xylanase and citric acid on the performance, nutrient retention, and characteristics of gastrointestinal tract of broilers fed low-phosphorus wheat-based diets. Poultry Science 90: 1975-1982.Google Scholar
GHANAATPARAST-RASHTI, M., SHARIATMADARI, F., KARIMITORSHIZI, M.A. and MOHITI-ASLI, M. (2016) Effects of dietary propionic acid, sodium citrate, and phytase on growth performance, mineral digestibility, and tibia properties in broilers. Journal of Applied Animal Research 44: 370-375.Google Scholar
GRASES, F., SIMONET, B.M., MARCH, J.G. and PRIETO, R.M. (2000) Inositol hexakisphosphate in urine: the relationship between oral intake and urinary excretion. BJU International 85: 138-142.Google Scholar
GRASES, F., SIMONET, B.M., VUCENIK, I., PRIETO, R.M., COSTA-BAUZÁ, A., MARCH, J.G. and SHAMSUDDIN, A.M. (2001) Absorption and excretion of orally administered inositol hexaphosphate (IP6 or phytate) in humans. BioFactors 15: 53-61.Google Scholar
GREINER, R. and KONIETZNY, U. (2012) Update on characteristics of commercial phytases, in: International Phytase Summit. Rome, pp. 96-107.Google Scholar
HARIHARAN, T. and GANGADEVI, P. (2015) Efficacy of citric acid and microbial phytase on the tibial characteristics, tibial and serum mineral concentrations in broiler chicken. Indian Journal of Animal Research 49: 328-332.Google Scholar
HUMER, E., SCHWARZ, C. and SCHEDLE, K. (2015) Phytate in pig and poultry nutrition. Journal of Animal Physiology and Animal Nutrition 99: 605-625.Google Scholar
HUTA, B., LENSBOEUR, J.J., LOWE, A.J., ZUBIETA, J. and DOYLE, R.P. (2012) Metal-citrate complex uptake and CitMHS transporters: From coordination chemistry to possible vaccine development. Inorganica Chimica Acta 393: 125-134.Google Scholar
JAIN, J., SAPNA and SINGH, B. (2016) Characteristics and biotechnological applications of bacterial phytases. Process Biochemistry 51: 159-169.Google Scholar
KHAN, S.H. and IQBAL, J. (2016) Recent advances in the role of organic acids in poultry nutrition. Journal of Applied Animal Research 44: 359-369.Google Scholar
LEI, X.G., WEAVER, J.D., MULLANEY, E., ULLAH, A.H. and AZAIN, M.J. (2013) Phytase, a new life for an “old” enzyme. Annual Review of Animal Biosciences 1: 283-309.Google Scholar
LIEM, A., PESTI, G.M. and EDWARDS, H.M. (2008) The effect of several organic acids on phytate phosphorus hydrolysis in broiler chicks. Poultry Science 87: 689-693.Google Scholar
MAENZ, D.D., ENGELE-SCHAAN, C.M., NEWKIRK, R.W. and CLASSEN, H.L. (1999) The effect of minerals and mineral chelators on the formation of phytase-resistant and phytase-susceptible forms of phytic acid in solution and in a slurry of canola meal. Animal Feed Science and Technology 81: 177-192.Google Scholar
MARKETS and MARKETS (2015) Industrial enzymes market by type (carbohydrases, proteases, non-starch polysaccharides & others), application (food & beverage, cleaning agents, animal feed & others), brands & by region - global trends and forecasts to 2020. Available at http://www.marketsandmarkets.com/Market-Reports/industrial-enzymes-market-237327836.html. (accessed 24 March 2018).Google Scholar
MATTEY, M. (1992) The production of organic acids. Critical Reviews in Biotechnology 12: 87-132.Google Scholar
MENEZES-BLACKBURN, D., GABLER, S. and GREINER, R. (2015) Performance of seven commercial phytases in an in vitro simulation of poultry digestive tract. Journal of Agricultural and Food Chemistry 63: 6142-6149.Google Scholar
MILEWSKA, M.J. (1988) Citric acid - its natural and synthetic derivatives. Zeitschrift für Chemie 28: 204-211.Google Scholar
MULLANEY, E.J. and ULLAH, A.H.J. (2003) The term phytase comprises several different classes of enzymes. Biochemical and Biophysical Research Communications 312: 179-184.Google Scholar
NOURMOHAMMADI, R., HOSSEINI, S.M., FARHANGFAR, H. and BASHTANI, M. (2012) Effect of citric acid and microbial phytase enzyme on ileal digestibility of some nutrients in broiler chicks fed corn-soybean meal diets. Italian Journal of Animal Science 11: e7.Google Scholar
ONYANGO, E.M., BEDFORD, M.R. and ADEOLA, O. (2005) Phytase activity along the digestive tract of the broiler chick: a comparative study of an Escherichia coli-derived and Peniophora lycii phytase. Canadian Journal of Animal Science 85: 61-68.Google Scholar
PARTANEN, K.H. and MROZ, Z. (1999) Organic acids for performance enhancement in pig diets. Nutrition Research Reviews 12: 117-145.Google Scholar
PINCKNEY, J.L., PAERL, H.W., TESTER, P. and RICHARDSON, T.L. (2001) The role of nutrient loading and eutrophication in estuarine ecology. Environmental Health Perspectives 109: 699-706.Google Scholar
RAFACZ-LIVINGSTON, K.A., MARTINEZ-AMEZCUA, C., PARSONS, C.M., BAKER, D.H. and SNOW, J. (2005a) Citric acid improves phytate phosphorus utilisation in crossbred and commercial broiler chicks. Poultry Science 84: 1370-1375.Google Scholar
RAFACZ-LIVINGSTON, K.A., PARSONS, C.M. and JUNGK, R.A. (2005b) The effects of various organic acids on phytate phosphorus utilisation in chicks. Poultry Science 84: 1356-1362.Google Scholar
RAVINDRAN, V. and SON, J. (2011) Feed enzyme technology: present status and future developments. Recent Patents on Food, Nutrition & Agriculture 3: 102-109.Google Scholar
SELLE, P.H., COWIESON, A.J., COWIESON, N.P. and RAVINDRAN, V. (2012) Protein-phytate interactions in pig and poultry nutrition: a reappraisal. Nutrition Research Reviews 25: 1-17.Google Scholar
SINGH, M. and KRIKORIAN, A.D. (1982) Inhibition of trypsin activity in vitro by phytate. Journal of Agricultural and Food Chemistry 30: 799-800.Google Scholar
SLOMINSKI, B.A. (2011) Recent advances in research on enzymes for poultry diets. Poultry Science 90: 2013-2023.Google Scholar
SNOW, J.L., BAKER, D.H. and PARSONS, C.M. (2004) Phytase, citric acid, and 1α-hydroxycholecalciferol improve phytate phosphorus utilisation in chicks fed a corn-soybean meal diet. Poultry Science 83: 1187-1192.Google Scholar
SUIRYANRAYNA, M.V.A.N. and RAMANA, J.V. (2015) A review of the effects of dietary organic acids fed to swine. Journal of Animal Science and Biotechnology 6: 45-55.Google Scholar
SUZUKI, U., YOSHIMURA, K. and TAKAISHI, M. (1907) About the enzyme “phytase”, which splits anhydro-oxy-methylene diphosphoric acid. Bulletin of the College of Agriculture, Tokyo Imperial University 1: 503-512.Google Scholar
TAHERI, H.R., ADIBNIA, S., JABBARI, Z., SHAHIR, M.H. and HOSSEINI, S.A. (2015) Effect of high-dose phytase and citric acid, alone or in combination, on growth performance of broilers given diets severely limited in available phosphorus. British Poultry Science 56: 708-715.Google Scholar
TAMIM, N.M., ANGEL, R. and CHRISTMAN, M. (2004) Influence of dietary calcium and phytase on phytate phosphorus hydrolysis in broiler chickens. Poultry Science 83: 1358-1367.Google Scholar
TAZISONG, I.A., SENWO, Z.N. and HE, Z. (2015) Phosphatase hydrolysis of organic phosphorus compounds. Advances in Enzyme Research 03: 39-51.Google Scholar
THORNE, M., THOMPSON, L. and JENKINS, D. (1983) Factors affecting starch digestibility and the glycemic response with special reference to legumes. The American Journal of Clinical Nutrition 38: 481-488.Google Scholar
VAN DER AAR, P.J., MOLIST, F. and VAN DER KLIS, J.D. (2017) The central role of intestinal health on the effect of feed additives on feed intake in swine and poultry. Animal Feed Science and Technology 233: 64-75.Google Scholar
VATS, P. and BANERJEE, U.C. (2004) Production studies and catalytic properties of phytases (myo-inositolhexakisphosphate phosphohydrolases): an overview. Enzyme and Microbial Technology 35: 3-14.Google Scholar
VIEIRA, B.S., SILVA, F.G., OLIVEIRA, C.F.S., CORREA, A.B., CARAMORI, J.G. (Jr) and CORREA, G.S.S. (2017) Does citric acid improve performance and bone mineralisation of broilers when combined with phytase? A systematic review and meta-analysis. Animal Feed Science and Technology 232: 21-30.Google Scholar
WILKINSON, S.J., WALK, C.L., BEDFORD, M.R. and COWIESON, A.J. (2013) Influence of conditioning temperature on the postpellet recovery and efficacy os 2 microbial phytases for broiler chicks. Journal of Applied Poultry Research 22: 308-313.Google Scholar
WILKINSON, S.J., SELLE, P.H., BEDFORD, M.R. and COWIESON, A.J. (2014) Separate feeding of calcium improves performance and ileal nutrient digestibility in broiler chicks. Animal Production Science 54: 172-178.Google Scholar
WOYENGO, T.A., SLOMINSKI, B.A. and JONES, R.O. (2010) Growth performance and nutrient utilisation of broiler chickens fed diets supplemented with phytase alone or in combination with citric acid and multicarbohydrase. Poultry Science 89: 2221-2229.Google Scholar
YIN, X., LI, J., SHIN, H., DU, G., LIU, L. and CHEN, J. (2015) Metabolic engineering in the biotechnological production of organic acids in the tricarboxylic acid cycle of microorganisms: advances and prospects. Biotechnology Advances 33: 830-841.Google Scholar
ZHITNITSKY, D., ROSE, J. and LEWINSON, O. (2017) The highly synergistic, broad spectrum, antibacterial activity of organic acids and transition metals. Scientific Reports 7: 44554.Google Scholar
ZYLA, K., LEDOUX, D.R. and VEUM, T.L. (1995) Complete enzymic dephosphorylation of corn-soybean meal feed under simulated intestinal conditions of the turkey. Journal of Agricultural and Food Chemistry 43: 288-294.Google Scholar