Skip to main content Accessibility help

Stereotactic Limbic Leucotomy: A Preliminary Report on Forty Patients

  • Desmond Kelly (a1), Alan Richardson (a1), Nita Mitchell-Heggs (a1), Juliet Greenup (a1), Char-nie Chen (a1) and R. Julian Hafner (a1)...


The neurophysiological aspects and operative technique of stereotactic limbic leucotomy have been described in a previous paper (Kelly, Richardson and Mitchell-Heggs, 1973). The present investigation is a prospective study designed to assess the results of such surgery in a group of 40 severely ill psychiatric patients, who had failed to respond satisfactorily to every other type of treatment. The results have been assessed clinically, psychologically and physiologically, in a very detailed way, at six weeks; a similar follow-up at one year is in progress. A comparison is made between the results of the present series and those of a previous: study (Kelly et al., 1972), in which more extensive leucotomy operations were carried out, and similar means of assessment were employed.



Hide All
Beck, A., Ward, C., Mendelson, M., Mork, J., and Erbaugh, J. (1961). ‘An inventory for measuring depression.Archives of General Psychiatry, 4, 561–71.
Crown, S., and Crisp, A. (1966). ‘A short clinical diagnostic self-rating scale for psychoneurotic patients.British Journal of Psychiatry, 112, 917–23.
Eysenck, H. (1959). Manual of the Maudsley Personality Inventory. London.
Freeman, W. (1971). ‘Frontal lobotomy in early schizophrenia. Long follow-up in 415 cases.British Journal of Psychiatry, 119, 621–4.
Hamilton, M. (1959). ‘The assessment of anxiety states by rating.British Journal of Medical Psychology, 32, 50–9.
Hamilton, M. (1967). ‘Development of a rating scale for primary depressive illness.British Journal of Social and Clinical Psychology, 6, 278–96.
Jackson, H. (1954). ‘Leucotomy—a recent development.Journal of Mental Science, 100, 62–5.
Kelly, D. H. W. (1967). ‘The technique of forearm plethysmography for assessing anxiety.Journal of Psychosomatic Research, 10, 373–82.
Kelly, D. H. W. (1972). ‘Physiological changes during operations on the limbic system in man.Conditional Reflex. 7, 127–38.
Kelly, D. H. W., Pik, R., and Chen, C. (1973). ‘A psychological and physiological evaluation of the effects of intravenous diazepam.British Journal of Psychiatry. In press.
Kelly, D. H. W., Richardson, A., and Mitchell-Heggs, N. (1973). ‘Stereotactic Limbic Leucotomy: Neurophysiological aspects and operative technique.British Journal of Psychiatry, 122, 133–40.
Kelly, D. H. W., Walter, C. J. S., and Sargant, W. (1966). ‘Modified leucotomy assessed by forearm blood flow an other measurements.British Journal of Psychiatry, 112, 871–81.
Kelly, D. H. W., Walter, C. J. S., Mitchell-Heggs, N., and Sargant, W. (1972). ‘Modified leucotomy assessed clinically, physiologically and psychologically at six weeks and eighteen months.British Journal of Psychiatry, 120, 1929.
McKisssock, W. (1959). ‘Discussion on psychosurgery.Proceedings of the Royal Society of Medicine, 52, 206–9.
Pippard, J. (1955). ‘Rostral leucotomy: a report on 240 cases personally followed up after 1f12 to 5 years.Journal of Mental Science, 101, 756–73.
Ström-Olsen, R., and Carlisle, S. (1971). ‘Bi-frontal stereotactic tractotomy. A follow-up study.British Journal of Psychiatry, 118, 141–54.
Taylor, J. (1953). ‘A personality scale of manifest anxiety.Journal of Abnormal and Social Psychology, 48, 285–90.
Walter, C. J. S., Mitchell-Hegos, N., and Sargant, W. (1972). ‘Modified narcosis, ECT and antidepressant drugs: a review of technique and immediate outcome of 679 courses of combined treatment in 484 patients’, British Journal of Psychiatry. 120, 651–62.
Wechsler, D. (1955). Manual for the Wechsler Adult Intelligence Scale. New York.


Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed

Stereotactic Limbic Leucotomy: A Preliminary Report on Forty Patients

  • Desmond Kelly (a1), Alan Richardson (a1), Nita Mitchell-Heggs (a1), Juliet Greenup (a1), Char-nie Chen (a1) and R. Julian Hafner (a1)...
Submit a response


No eLetters have been published for this article.


Reply to: Submit a response

Your details

Conflicting interests

Do you have any conflicting interests? *