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Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging

  • Therese Van Amelsvoort (a1), Nicole Schmitz (a2), Eileen Daly (a3), Quinton Deeley (a3), Hugo Critchley (a4), Jayne Henry (a3), Dene Robertson (a3), Michael Owen (a5), Kieran C. Murphy (a6) and Declan G. Murphy (a3)...

Summary

We studied the functional neuroanatomy of social behaviour in velo-cardio-facial syndrome (VCFS) using a facial emotional processing task and functional magnetic resonance imaging in adults with this syndrome and controls matched for age and IQ. The VCFS group had less activation in the right insula and frontal brain regions and more activation in occipital regions. Genetically determined abnormalities in pathways including those involved in emotional processing may underlie deficits in social cognition in people with VCFS.

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Corresponding author

Therese van Amelsvoort, Department of Psychiatry Academic Medical Centre, Amsterdam, The Netherlands. Email: t.a.vanamelsvoort@amc.uva.nl

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Declaration of interest

None. The study was part funded by the Stanley Foundation and the Medical Research Council.

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References

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Processing facial emotions in adults with velo-cardio-facial syndrome: functional magnetic resonance imaging

  • Therese Van Amelsvoort (a1), Nicole Schmitz (a2), Eileen Daly (a3), Quinton Deeley (a3), Hugo Critchley (a4), Jayne Henry (a3), Dene Robertson (a3), Michael Owen (a5), Kieran C. Murphy (a6) and Declan G. Murphy (a3)...
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