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Personality disorder and psychopathology in Tourette's syndrome: A controlled study

Published online by Cambridge University Press:  03 January 2018

Mary M. Robertson*
Affiliation:
University College London Medical School, and National Hospital for Neurology and Neurosurgery
Sube Banerjee
Affiliation:
Institute of Psychiatry
Paul J. Fox-Hiley
Affiliation:
Camden and Islington NSH Trust, National Hospital for Neurology and Neurosurgery
Charles Tannock
Affiliation:
Camden and Islington NSH Trust, National Hospital for Neurology and Neurosurgery
*
Dr M. M. Robertson, Reader in Neuropsychiatry, University College London Medical School, Department of Psychiatry and Behavioural Sciences, Middlesex Hospital Site, Mortimer Street, London WIN 8AA. Tel: (44) 171 380 9471 Fax: (44) 171 323 1459

Abstract

Background

Some specialists associate a wide variety of psychopathologies with Tourette's syndrome (TS), while others suggest that there is no psychopathology specifically associated. Few controlled studies have been conducted to address this issue, and none has investigated personality disorder in TS.

Method

Adults with TS and controls were evaluated using standardised psychiatric rating scales, including self-rated (STPCD) and clinician-rated (SCID–II) assessments of personality disorder, to investigate associations between personality disorder, other psychopathology and TS.

Results

Significantly more TS patients (25/39 (64%)) than controls (2/34 (6%)) had one or more personality disorders. TS subjects were also more likely to have more personality disorders. TS patients had significantly more depression, anxiety and obsessionality than controls. The SCID–II and STCPD were moderately well correlated.

Conclusions

TS patients have a high prevalence of personality disorder and psychopathology when compared with controls. These results are the first to suggest a high level of personality disorder in a TS clinic population.

Type
Papers
Copyright
Copyright © 1997 The Royal College of Psychiatrists 

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References

American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R). Washington, DC: APA.Google Scholar
American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (4th edn) (DSM–IV). Washington, DC: APA.Google Scholar
Beck, A. T., Ward, C. H., Mendelson, M., et al (1961) An inventory for measuring depression. Archives of General Psychiatry, 4, 561571.Google Scholar
Berkson, J. (1944) Limitations of the application of fourfold table analysis to hospital data. Biometrics, 2, 4751.CrossRefGoogle Scholar
Comings, D. E. (1990) Tourette Syndrome and Human Behavior. Duarte: Hope Press.Google Scholar
Comings, D. E. & Comings, B. G. (1987) A controlled study of Tourette syndrome. 1. Attention deficit disorder, learning disorders and school problems. American Journal of Human Genetics, 41, 701741.Google Scholar
Dowson, J. H. (1992) Assessment of DSM–III–R personality disorders, by self report questionnaire: the role of informants and a screening test for co-morbid personality disorders (STCPD). British Journal of Psychiatry, 161, 344352.CrossRefGoogle Scholar
Flick, S. N., Roy-Byrne, P. P., Cowley, D. S., et al (1993) DSM–III–R personality disorders in a mood and anxiety disorders clinic: Prevalence, comorbidity, and clinical correlates. Journal of Affective Disorders, 27, 7179.CrossRefGoogle Scholar
Lackmen, J. F., Riddle, M. A., Hardin, M. T., et al (1989) The Yale Global Tic Severity Scale: Initial testing of a clinician-rated scale of tic severity. Journal of the American Academy of Child and Adolescent Psychiatry, 28, 566573.CrossRefGoogle Scholar
McMahon, W. M., Leppert, M., Filloux, F., et al (1992) Tourette symptoms in 161 related family members. In Advances in Neurology, 58 (eds T. N. Chase, A. J. Friedhoff & D. J. Cohen), pp 159165. New York: Raven Press.Google Scholar
Nussbaum, D. & Rogers, R. (1992) Screening psychiatric patients for Axis II disorders. Canadian Journal of Psychiatry, 37, 658660.CrossRefGoogle ScholarPubMed
Robertson, M. M. (1994) Annotation: Gilles de la Tourette syndrome – an update. Journal of Child Psychology and Psychiatry, 35, 597611.Google Scholar
Robertson, M. M. (1995) The relationship between Gilles de la Tourette's Syndrome and obsessive compulsive disorder. Journal of Serotonin Research, Suppl. 1, 4962.Google Scholar
Robertson, M. M., Channon, S., Baker, J., et al (1993) The psychopathology of Gilles de la Tourette syndrome. British Journal of Psychiatry, 162, 114117.Google Scholar
Robertson, M. M. & Eapen, V. (1996) The National Hospital Interview Schedule for the assessment of Gilles de la Tourette syndrome. International Journal of Methods in Psychiatric Research, 6, 203226.Google Scholar
Robertson, M. M. & Gourdie, A. (1990) Familial Tourette's syndrome in a large British pedigree: associated psychopathology, severity and potential for linkage analysis. British Journal of Psychiatry, 156, 515521.Google Scholar
Shapiro, A. K., Shapiro, E., Bruun, R. D., et al (1978) Giles de la Tourette's Syndrome. New York: Raven Press.Google Scholar
Shea, M. T., Widiger, T. A. & Klein, M. H. (1992) Comorbidity of personality disorders and depression: implications for treatment. Journal of Consulting and Clinical Psychology, 60, 857868.Google Scholar
Snowdon, J. (1980) A comparison of written and postbox forms of the Leyton Obsessional Inventory. Psychological Medicine, 10, 165170.CrossRefGoogle ScholarPubMed
Spielberger, C. D., Gorsuch, R. L. & Lushene, R. E. (1970) Manual for the State-Trait Anxiety Inventory (‘Self-evaluational Questionnaire’). Palo Alto. CA: Consulting Psychologists Press.Google Scholar
Spitzer, R. L., Williams, J. B. W. & Gibbon, M. (1987) Structured Clinical Interview for DSM–III–R – Patient version. Research Department, New York State Psychiatric Institute, New York: Biometrics.Google Scholar
Stone, M. H. (1993) Long-term outcome in personality disorders. British Journal of Psychiatry, 162, 299313.Google Scholar
Tyrer, P., Seivewright, N., Ferguson, B., et al (1993) The Nottingham study of neurotic disorder. Effect of personality status on response to drug treatment, cognitive therapy and self-help over two years. British Journal of Psychiatry. 162, 219226.CrossRefGoogle ScholarPubMed
World Health Organization (1992) International Classification of Diseases and Health Related Problems – Tenth Revision. Geneva: WHO.Google Scholar
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