Skip to main content Accessibility help
×
Home

Opiate Withdrawal Symptoms in Response to 10-Day and 21-Day Methadone Withdrawal Programmes

  • Michael Gossop (a1), Paul Griffiths (a1), Brendan Bradley (a2) and John Strang (a3)

Abstract

This study investigates and compares the responses of 132 opiate addicts to a 10-day or a 21-day in-patient oral methadone withdrawal regime. For both groups, symptom severity (on the Opiate Withdrawal Scale) steadily increased through the methadone withdrawal phase, and peaked near the point of completion of the prescribed drug, declining slowly thereafter. Patients on the 10-day programme reported significantly higher peak withdrawal scores than those on the 21-day programme. Although the proportions who completed detoxification were similar, there was a significantly higher drop-out rate immediately after detoxification for the 10-day group. The possible benefits and handicaps of the two withdrawal schedules are considered and recommendations are proposed for further refinement of the present widely adopted approach.

Copyright

Corresponding author

Correspondence

References

Hide All
Bradley, B. & Gossop, M. (1982) Differences in attitudes towards drug taking among drug addicts: implications for treatment. Drug and Alcohol Dependence, 10, 361366.
Bradley, B., Gossop, M., Phillips, G. et al (1987) The development of an opiate withdrawal scale (OWS). British Journal of Addiction, 82, 11391142.
Gossop, M., Eiser, J. R. & Ward, E. (1982) The addicts' perceptions of their own drug taking: implications for the treatment of drug dependence. Addictive Behaviours, 7, 189194.
Gossop, M. & Bradley, B. (1984) Insomnia among addicts during supervised withdrawal from opiates: a comparison of oral methadone and electrostimulation. Drug and Alcohol Dependence, 13, 191198.
Gossop, M., Bradley, B., Strang, J., et al (1984) The clinical effectiveness of electrostimulation vs oral methadone in managing opiate withdrawal. British Journal of Psychiatry, 144, 203208.
Gossop, M., Johns, A. & Green, L. (1986) Opiate withdrawal: in patient vs outpatient programmes and preferred vs random assignment to treatment. British Medical Journal, 293, 103104.
Gossop, M., Green, L., Phillips, G., et al (1987a) What happens to opiate addicts immediately after treatment: a prospective follow-up study. British Medical Journal, 294, 13771380.
Gossop, M., Bradley, B. & Phillips, G. (1987b) An investigation of withdrawal symptoms shown by opiate addicts during and subsequent to a 21-day in-patient methadone detoxification procedure. Addictive Behaviours, 12, 16.
Green, L. & Gossop, M. (1988) The effects of information on the opiate withdrawal syndrome. British Journal of Addiction, 83, 304309.
Isbell, H. & Vogel, V. H. (1948) The addiction liability of methadone and its use in the treatment of the morphine abstinent syndrome. American Journal of Psychiatry, 105, 909.
Johns, A. & Gossop, M. (1985) Prescribing methadone for the opiate addict: a problem of dosage conversion. Drug and Alcohol Dependence, 16, 6166.
Kleber, H. D. (1981) Detoxification from narcotics. In Substance Abuse (eds Lowinson, J. & Ruiz, P.), pp 317338. Baltimore: Williams and Wilkins.
Kleber, H. D., Gold, M. S. & Riordan, C. E. (1980) The use of Clonidine in detoxification from opiates. UN Bulletin on Narcotics, 32, 110.
Lipton, D. S. & Maranda, M. J. (1983) Detoxification from heroin dependency: an overview of method and effectiveness. In Evaluation of Drug Treatment Programme (ed. Stimmel, B.), pp 3155. New York: Haworth Press.
Phillips, G. T., Gossop, M. & Bradley, B. (1986) The influence of psychological factors on the opiate withdrawal syndrome. British Journal of Psychiatry, 149, 235238.

Opiate Withdrawal Symptoms in Response to 10-Day and 21-Day Methadone Withdrawal Programmes

  • Michael Gossop (a1), Paul Griffiths (a1), Brendan Bradley (a2) and John Strang (a3)

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.

Opiate Withdrawal Symptoms in Response to 10-Day and 21-Day Methadone Withdrawal Programmes

  • Michael Gossop (a1), Paul Griffiths (a1), Brendan Bradley (a2) and John Strang (a3)
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *