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Neuroendocrine Rhythms in a Patient with the Kleine–Levin Syndrome

  • C. Thompson (a1), R. Obrecht (a2), C. Franey (a3), J. Arendt (a3) and S. A. Checkley (a4)...


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Arendt, J., Wetterberg, L., Heyden, T., Sisonenko, P. C. & Paunier, L. (1977) Radioimmunoassay of melatonin: human serum and cerebrospinal fluid. Hormone Research, 8, 6575.
Boyar, R. M., Karen, S., Finkelstein, J. W., Perlow, M., Sassin, J. F., Fukushima, D. K., Weitzman, E. D. & Hellman, L. (1974) Hypothalamic pituitary function in diverse hyperprolactinaemic states. Journal of Clinical Investigations, 53, 15881598.
Critchley, M. (1962) Periodic hypersomnia and megaphagia in adolescent males. Brain, 85, 627656.
Elian, M. & Bornstein, B. (1969) The Kleine-Levin syndrome with intermittent abnbormality on the EEC. Electroencephalography and Clinical Neurophysiology, 27, 601604.
Gilligan, B. S. (1973) Periodic megaphagia and hypersomnia—an example of the Kleine-Levin syndrome in an adolescent girl. Proceedings of the Australian Association of Neurologists, 9, 6772.
Jeffries, J. J. & Lefebvre, A. (1973) Depression and mania associated with the Kleine-Levin-Critchley syndrome. Canadian Psychiatric Association Journal, 18, 439444.
Klein, D. C. (1979) Circadian rhythms in the pineal gland. In Endocrine Rhythms (ed. Krieger, D. T.). New York: Raven.
Kleine, W. (1925) Periodische Schlafsucht. Monatsschrift für Psychiatric und Neurologie, 57, 285320.
Krieger, D. T. (1973) Pathophysiology of central nervous system regulation of anterior pituitary function. In Biology of Brain Dysfunction (ed. Gaul, ). New York: Plenum.
Lavie, P., Gadoth, N., Gordon, C. R., Goldhammer, G. & Bechar, M. (1979) Sleep patterns in Kleine-Levin syndrome. Electroencephalography and Clinical Neurophysiology, 47, 369371.
Levin, M. (1936) Periodic somnolence and morbid hunger: a new syndrome. Brain, 59, 494504.
Moore, R. Y. & Elchler, V. B. (1972) Loss of a circadian adrenal corticosterone rhythm following suprachiasmatic lesions in the rat. Brain Research, 42, 201206.
Moore, R. Y. & Klein, D. C. (1974) visual pathways and the central neural control of a circadian rhythm in pineal serotonin-N-acetyltransferase activity. Brain Research, 71, 1733.
Moore, R. Y. (1979) Anatomy of central neural mechanisms regulating endocrine rhythms. In Endocrine Rhythms (ed. Krieger, D. T.). New York: Raven.
Pohl, O. & Maits, G. (1968) Hypomanic psychosis alternating with periodical hypersomnia. Psychiatria Clinica, 1, 120124.
Popoviciu, L. & Corfarice, O. (1972) Etude clinique et polygraphique au cours du nyclhemere d'un case de syndrome de Kleine-Levin-Critchley. Revue Roumaine de Neurologie, 9, 229248.
Sassin, J. F., Frantz, A. G., Kapen, S. & Weitzman, E. D. (1973) The nocturnal rise of human prolactin is dependent on sleep. Journal of Clinical Endocrinology and Metabolism, 37, 436440.
Thacore, V. R., Ahmed, M. & Oswald, I. (1969) The EEG in a case of periodic hypersomnia. Electroencephalography and Clinical Neurophysiology, 27, 605606.
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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
  • URL: /core/journals/the-british-journal-of-psychiatry
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Neuroendocrine Rhythms in a Patient with the Kleine–Levin Syndrome

  • C. Thompson (a1), R. Obrecht (a2), C. Franey (a3), J. Arendt (a3) and S. A. Checkley (a4)...
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