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The Independence of Neurotic and Endogenous Depression

  • N. McConaghy (a1), A. D. Joffe (a2), B. Murphy (a2), W. R. Kingston (a3), H. G. Stevenson (a3), I. Atkinson (a3), E. Cole (a3) and L. A. Fennessy (a4)...

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This paper presents a replication of a study by Kiloh and Garside (1963). These workers carried out a factor analysis of 35 clinical features of 143 depressed patients. They demonstrated the presence of a factor which showed strong positive loadings with the clinical features classically accepted as characterizing neurotic depression and strong negative loadings with the clinical features characterizing endogenous depression. Of the 143 patients, 92 were diagnosed as more definitely suffering from endogenous or neurotic depression. Correlation coefficients were calculated between the diagnosis in these 92 cases and each clinical feature.

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Abraham, H. C., Kanter, V. B., Rosen, I., and Standen, J. L. (1963). “A controlled clinical trial of imipramine (‘Tofranil’) with out-patients.” Brit. J. Psychiat., 109, 286293.
Brown, M. W., Kreeger, L. C., and Kazamias, N. G. (1963). “A clinical trial of amitriptyline in treatment of depressive states.” Ibid., 109, 692694.
Carney, M. W. P., Roth, M., and Garside, R. F. (1965). “The diagnosis of depressive syndromes and the prediction of E.C.T. response.” Ibid., 111, 659674.
Costello, G. G., and Selby, M. M. (1965). “The relationships between sleep patterns and reactive and endogenous depressions.” Ibid., 111, 497501.
Fish, F. (1965). In: Proceedings of the Leeds Symposium on Behavioural Disorders (ed. Jenner, ), Dagenham, p. 198.
Hordern, A., Holt, N. F., Burt, C. G., and Gordon, W. F. (1963). “Amitriptyline in depressive states. Phenomenology and prognostic considerations.” Brit. J. Psychiat., 109, 815825.
Kiloh, L. G., Ball, J. R. B., and Garside, R. F. (1962). “Prognostic factors in treatment of depressive states with impramine.” Brit. med. J., i, 12251227.
Kiloh, L. G., and Garside, R. F. (1963). “The independence of neurotic and endogenous depression.” Ibid., 109, 451463.
McConaohy, N., Kingston, W. R., Stevenson, H. G., Atkinson, I., Cole, E., and Fennessy, L. A. (1965). “A controlled trial comparing amitriptyline and protriptyline in the treatment of out-patient depressives.” Med. J. Aust., 2, 403405.
Mendels, J. (1965). “Electroconvulsive therapy and depression.” Brit. J. Psychiat., 111, 675681.
Spear, F. G., Hall, P., and Stirland, J. D. (1964). “A comparison of subjective responses to imipramine and tranylcypromine.” Ibid., 110, 5355.

The Independence of Neurotic and Endogenous Depression

  • N. McConaghy (a1), A. D. Joffe (a2), B. Murphy (a2), W. R. Kingston (a3), H. G. Stevenson (a3), I. Atkinson (a3), E. Cole (a3) and L. A. Fennessy (a4)...

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The Independence of Neurotic and Endogenous Depression

  • N. McConaghy (a1), A. D. Joffe (a2), B. Murphy (a2), W. R. Kingston (a3), H. G. Stevenson (a3), I. Atkinson (a3), E. Cole (a3) and L. A. Fennessy (a4)...
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