Skip to main content Accessibility help
×
Home

Impact of childhood trauma on risk of relapse requiring psychiatric hospital admission for psychosis

  • N. Petros (a1), E. Foglia (a2), E. Klamerus (a2), S. Beards (a3), R. M. Murray (a4) and S. Bhattacharyya (a4)...

Summary

Relapse in psychosis typically necessitates admission to hospital placing a significant financial burden on the health service. Exposure to childhood trauma is associated with an increased risk of psychosis, however, the extent to which this influences relapse is unclear. This report summarises current research investigating the influence of childhood trauma on relapse requiring psychiatric hospital admission for psychosis. Seven studies were included; two revealed a positive association between childhood trauma and relapse admission, two studies found a negative relationship and three found no significant difference. Inconsistent current evidence suggests a need for further research in this area.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Impact of childhood trauma on risk of relapse requiring psychiatric hospital admission for psychosis
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Impact of childhood trauma on risk of relapse requiring psychiatric hospital admission for psychosis
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Impact of childhood trauma on risk of relapse requiring psychiatric hospital admission for psychosis
      Available formats
      ×

Copyright

Corresponding author

Sagnik Bhattacharyya, M6.01.04, Department of Psychosis Studies, Box P067, Institute of Psychiatry, Psychology & Neuroscience, King's College London, 16 De Crespigny Park, London SE5 8AF, UK. Email: sagnik.2.bhattacharyya@kcl.ac.uk

Footnotes

Hide All

These authors are joint second authors.

Declaration of interest

None.

Footnotes

References

Hide All
1 Robinson, D, Woerner, M, Alvir, J, Bilder, R, Goldman, R, Geisler, S, et al. Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Arch Gen Psychiatry 1999; 56: 241–7.
2 Almond, S, Knapp, M, Francois, C, Toumi, M, Brugha, T. Relapse in schizophrenia: costs, clinical outcomes and quality of life. Br J Psychiatry 2004; 184: 346–51.
3 Neria, Y, Bromet, EJ, Carlson, GA, Naz, B. Assaultive trauma and illness course in psychotic bipolar disorder: findings from the Suffolk county mental health project. Acta Psychiatr Scand 2005; 111: 380–3.
4 Greenfield, SF, Strakowski, SM, Tohen, M, Batson, SC, Kolbrener, ML. Childhood abuse in first-episode psychosis. Br J Psychiatry 1994; 164: 831–4.
5 Varese, F, Smeets, F, Drukker, M, Lieverse, R, Lataster, T, Viechtbauer, W, et al. Childhood adversities increase the risk of psychosis: a meta-analysis of patient-control, prospective and cross-sectional cohort studies. Schizophr Bull 2012; 38: 661–71.
6 Beards, S, Gayer-Anderson, C, Borges, S, Dewey, ME, Fisher, HL, Morgan, C. Life events and psychosis: a review and meta-analysis. Schizophr Bull 2013; 39: 740–7.
7 Alvarez, MJ, Roura, P, Oses, A, Foguet, Q, Sola, J, Arrufat, FX. Prevalence and clinical impact of childhood trauma in patients with severe mental disorders. J Nerv Ment Dis 2011; 199: 156–61.
8 Larsson, S, Aas, M, Klungsoyr, O, Agartz, I, Mork, E, Steen, NE, et al. Patterns of childhood adverse events are associated with clinical characteristics of bipolar disorder. BMC Psychiatry 2013; 13: 97.
9 Schenkel, LS, Spaulding, WD, DiLillo, D, Silverstein, SM. Histories of childhood maltreatment in schizophrenia: relationships with premorbid functioning, symptomatology, and cognitive deficits. Schizophr Res 2005; 76: 273–86.
10 Garno, JL, Goldberg, JF, Ramirez, PM, Ritzler, BA. Impact of childhood abuse on the clinical course of bipolar disorder. Br J Psychiatry 2005; 186: 121–5.
11 Conus, P, Cotton, S, Schimmelmann, BG, Berk, M, Daglas, R, McGorry, PD, et al. Pretreatment and outcome correlates of past sexual and physical trauma in 118 bipolar I disorder patients with a first episode of psychotic mania. Bipolar Disord 2010; 12: 244–52.
12 Cutajar, MC, Mullen, PE, Ogloff, JR, Thomas, SD, Wells, DL, Spataro, J. Schizophrenia and other psychotic disorders in a cohort of sexually abused children. Arch Gen Psychiatry 2010; 67: 1114–9.
13 Brown, GR, McBride, L, Bauer, MS, Williford, WO. Impact of childhood abuse on the course of bipolar disorder: a replication study in U.S. veterans. J Affect Disord 2005; 89: 5767.
14 Bauer, MS, Shea, N, McBride, L, Gavin, C. Predictors of service utilization in veterans with bipolar disorder: a prospective study. J Affect Disord. 1997; 44: 159–68.
15 Trotta, A, Murray, RM, Fisher, HL. The impact of childhood adversity on the persistence of psychotic symptoms: a systematic review and meta-analysis. Psychol Med 2015; 45: 2481–98.
16 Read, J, Hammersley, P, Rudegeair, T. Why, when and how to ask about childhood abuse. Adv Psychiatr Treat 2007; 13: 101–10.
17 Schoeler, T, Monk, A, Sami, MB, Klamerus, E, Foglia, E, Brown, R, et al. Continued versus discontinued cannabis in patients with psychosis: a systematic review and meta-analysis. Lancet Psychiatry 2016; 3: 215–25.
Type Description Title
PDF
Supplementary materials

Petros et al. supplementary material
Supplementary Material

 PDF (665 KB)
665 KB

Impact of childhood trauma on risk of relapse requiring psychiatric hospital admission for psychosis

  • N. Petros (a1), E. Foglia (a2), E. Klamerus (a2), S. Beards (a3), R. M. Murray (a4) and S. Bhattacharyya (a4)...

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed

Impact of childhood trauma on risk of relapse requiring psychiatric hospital admission for psychosis

  • N. Petros (a1), E. Foglia (a2), E. Klamerus (a2), S. Beards (a3), R. M. Murray (a4) and S. Bhattacharyya (a4)...
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *