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First-episode schizophrenia, bipolar disorder and other psychoses in a rural Irish catchment area: Incidence and gender in the Cavan–Monaghan study at 5 years

  • Paul J. Scully (a1), John F. Quinn (a1), Maria G. Morgan (a1), Anthony Kinsella (a2), Eadbhard O'Callaghan (a3), John M. Owens (a1) and John L. Waddington (a4)...

Abstract

Background

The potential of first-episode studies in schizophrenia is maximised through systematic epidemiological, clinical and biological comparisons between homogeneous populations of the psychoses.

Aims

To conduct prolonged accrual of ‘all’ cases of non-affective and affective psychotic illness on an epidemiologically complete basis.

Method

Within the region covered by Cavan–Monaghan psychiatric service (population 102 810), all putative cases of first-episode psychosis were diagnosed using DSM–IV.

Results

From 1995 to 2000, 69 cases of psychosis were ascertained, the incidence being 2.3-fold lower in females than in males. On resolving the ‘core’ diagnoses of schizophrenia and bipolar disorder, incidence of schizophrenia among women was 7.5-fold lower than among men whereas incidence of bipolar disorder among women was 6.6-fold lower than among men.

Conclusions

This homogeneous population, which eliminates factors associated with urbanicity and minimises confounding factors such as socioeconomic, ethnic and geographical diversity, shows a markedly reduced incidence among females both of schizophrenia and of bipolar disorder.

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Copyright

Corresponding author

Professor John L. Waddington, Department of Clinical Pharmacology, Royal College of Surgeons in Ireland, St Stephen's Green, Dublin 2, Ireland. Tel. +353 I 402 2245; fax: +353 1 402 2453; e-mail: jwadding@rcsi.ie

Footnotes

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Presented in part at the European First Episode Schizophrenia Network Meeting, Whistler BC, Canada, 27 April 2001.

Declaration of interest

Supported by the Stanley Medical Research Institute.

Footnotes

References

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First-episode schizophrenia, bipolar disorder and other psychoses in a rural Irish catchment area: Incidence and gender in the Cavan–Monaghan study at 5 years

  • Paul J. Scully (a1), John F. Quinn (a1), Maria G. Morgan (a1), Anthony Kinsella (a2), Eadbhard O'Callaghan (a3), John M. Owens (a1) and John L. Waddington (a4)...

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First-episode schizophrenia, bipolar disorder and other psychoses in a rural Irish catchment area: Incidence and gender in the Cavan–Monaghan study at 5 years

  • Paul J. Scully (a1), John F. Quinn (a1), Maria G. Morgan (a1), Anthony Kinsella (a2), Eadbhard O'Callaghan (a3), John M. Owens (a1) and John L. Waddington (a4)...
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