Hostname: page-component-848d4c4894-8kt4b Total loading time: 0 Render date: 2024-07-04T23:58:07.384Z Has data issue: false hasContentIssue false
  • English
  • Français

Down's Syndrome with Mania

Published online by Cambridge University Press:  02 January 2018

Edwin H. Cook Jr.  and
Bennett L. Leventhal
Edwin H. Cook Jr.*
Affiliation:
Child Psychiatry
Bennett L. Leventhal
Affiliation:
Child Psychiatry, Associate Chairman, Department of Psychiatry, University of Chicago
*
∗University of Chicago, 5841 S. Maryland (Box 411) Chicago, Illinois 60637, USA
Get access Rights & Permissions [Opens in a new window]

Extract

Sovner et al (1985) proposed that the presence of Down's Syndrome (DS) precludes the possibility of concomitant mama, and this is not a new claim, since Earl (1961) had stated that neither cyclothymia nor manic-depressive psychosis occurred in the mentally retarded. While Sovner et al conceded that cases of mania in individuals with DS may simply have gone unrecognised or unpublished, they felt this to be unlikely. However, lest this suggestion enter the canon, we present a previously unreported case of a young adult with both DS and recurrent mania.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 150 , Issue 2 , February 1987 , pp. 249 - 250
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Boullin, D. J. & O'Brien, R. A. (1971) Abnormalities of 5-hydroxytrytamine uptake and binding by blood platelets from children. Journal of Physiology, 212, 287–297.Google Scholar
Earl, C. J. C. (1961) Subnormal Personalities. Baltimore: Williams and Wilkins.Google Scholar
Lott, I. T., Murphy, D. L. & Chase, T. N. (1972) Down's syndrome-central monoamine turnover in patients with diminished serotonin. Neurology, 22, 961–912.Google Scholar
Parsons, J. A., May, J. G. & Menolascino, F. J. (1984) The nature and incidence of mental illness in mentally retarded individuals. In Handbook of Mental Illness in the Mentally Retarded (eds F. J. Menolascino & J. A. Stark), London: Plenum.Google Scholar
Pranoe, A. J., Wilson, I. C., Lynn, C. W. et al (1974) L-Tryptophan in mania. Archives of General Psychiatry, 30, 56–62.CrossRefGoogle Scholar
Rollin, H. R. (1946) Personality in mongolism with special reference to the incidence of catatonic psychosis. American Journal of Mental Deficiency, 51, 219–237.Google Scholar
Rosner, F., Ong, B. H., Paine, R. S. & Mahanand, D. (1965) Blood-serotonin activity in trisomic and translocation Down's syndrome. Lancet, i, 1191–1193.Google Scholar
Sovner, R. & Hurley, A. D. (1983) Do the mentally retarded suffer from affective illness? Archives of General Psychiatry, 40, 61–67.Google Scholar
Sovner, R. & Hurley, A. D. & Labrie, R. (1985) Is mania incompatible with Down's syndrome? British Journal of Psychiatry, 146, 319–320.CrossRefGoogle ScholarPubMed
Tu, J. & Partington, M. W. (1972) 5-Hydroxyindole levels in the blood and CSF in Down's syndrome, phenylketonuria and severe mental retardation. Developmental Medicine and Child Neurology, 14, 457–466.Google Scholar
Tu, J. & Zellweger, H. (1965) Blood-serotonin deficiency in Down's syndrome. Lancet, 2, 715–717.CrossRefGoogle ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.