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Clozapine in the Treatment of Psychotic Refractory Depression

Published online by Cambridge University Press:  02 January 2018

Daniel Dassa
Affiliation:
Department of Psychiatry, Timone Hospital, Rue St Pierre, 13385 Marseille, France
Arthur Kaladjian
Affiliation:
Department of Psychiatry, Timone Hospital, Rue St Pierre, 13385 Marseille, France
Jean M. Azorin
Affiliation:
Department of Psychiatry, Timone Hospital, Rue St Pierre, 13385 Marseille, France
Sebastien Giudicelli
Affiliation:
Department of Psychiatry, Timone Hospital, Rue St Pierre, 13385 Marseille, France

Abstract

A 40-year-old woman suffering from major depression with psychotic features was unresponsive to conventional therapy. After the administration of a wide range of drug treatments and ECT, she received clozapine. Depressive symptoms improved and psychotic features disappeared. It is suggested that clozapine could be efficient in psychotic refractory depression.

Type
Brief Reports
Copyright
Copyright © The Royal College of Psychiatrists 

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