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Traitement d'urgence des contaminations internes par les transuraniens. Une nouvelle formegalénique du Na3CaDTPA micronisé

Published online by Cambridge University Press:  17 June 2005

H. Tymen
Affiliation:
Service de protection radiologique des armées, BP 1, 00480 Armées, France.
D. Schoulz
Affiliation:
Commissariat à l'énergie atomique, DAM/DQS, BP 12, 91680 Bruyères le Châtel, France.
A. M. Caire-Maurisier
Affiliation:
Pharmacie centrale des armées, BP 2533, 45038 Orléans Cedex 1, France.
F. Chevrier
Affiliation:
Pharmacie centrale des armées, BP 2533, 45038 Orléans Cedex 1, France.
P. M. Curet
Affiliation:
Service de protection radiologique des armées, BP 1, 00480 Armées, France.
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Abstract

Emergency treatment of pulmonary contaminations by transuranium elements. A new galenic form of Na3CaDTPA. The emergency treatment of pulmonary contamination by plutonium and transuranium elements needs the early use of a chelator, the Na3CaDTPA under monocalcic trisodic form. The local administration of the active principle is carried out by an appliance, the Spinhaler$^{\circledR}$, which delivers the active principle under micronised form without any propelled gas. The French Military Health Service is the manufacturer which produces this treatment and has studied a modification of the galenic form of Na3CaDTPA to improve the intrapulmonary distribution. This treatment, without any secondary effect, is proposed even for a presumed pulmonary contamination. Its easy use allows an early administration for a large number of people supposed to be contaminated. However, it cannot take the place of the other forms of treatment, especially intraveinous, which needs a medical prescription in case of an established contamination.

Type
Research Article
Copyright
© EDP Sciences, 2000

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