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The effect of Chinese famine exposure in early life on dietary patterns and chronic diseases of adults

  • Jielin Zhou (a1), Jie Sheng (a2), Yong Fan (a1), Xingmeng Zhu (a1), Qi Tao (a1), Kaiyong Liu (a1), Chunqiu Hu (a1), Liang Ruan (a1), Linsheng Yang (a3), Fangbiao Tao (a2) and Sufang Wang (a1)...

Abstract

Objective

To assess the effect of famine exposure during early life on dietary patterns, chronic diseases, and the interaction effect between famine exposure and dietary patterns on chronic diseases in adulthood.

Design

Cross-sectional study. Dietary patterns were derived by factor analysis. Multivariate quantile regression and log-binomial regression were used to evaluate the impact of famine exposure on dietary patterns, chronic diseases and the interaction effect between famine exposure and dietary patterns on chronic diseases, respectively.

Setting

Hefei, China.

Participants

Adults aged 45–60 years (n 939).

Results

‘Healthy’, ‘high-fat and high-salt’, ‘Western’ and ‘traditional Chinese’ dietary patterns were identified. Early-childhood and mid-childhood famine exposure were remarkably correlated with high intake of the traditional Chinese dietary pattern. Compared with the non-exposed group (prevalence ratio (PR); 95 % CI), early-childhood (3·13; 1·43, 6·84) and mid-childhood (2·37; 1·05, 5·36) exposed groups showed an increased PR for diabetes, and the early-childhood (2·07; 1·01, 4·25) exposed group showed an increased PR for hypercholesterolaemia. Additionally, relative to the combination of non-exposed group and low-dichotomous high-fat and high-salt dietary pattern, the combination of famine exposure in early life and high-dichotomous high-fat and high-salt dietary pattern in adulthood had higher PR for diabetes (4·95; 1·66, 9·05) and hypercholesterolaemia (3·71; 1·73, 7·60), and significant additive interactions were observed.

Conclusions

Having suffered the Chinese famine in childhood might affect an individual’s dietary habits and health status, and the joint effect between famine and harmful dietary pattern could have serious consequences on later-life health outcomes.

Copyright

Corresponding author

*Corresponding author: Email wangsufangdev@126.com

Footnotes

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Jielin Zhou and Jie Sheng contributed equally to this work.

Footnotes

References

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