Skip to main content Accessibility help
×
Home

Diet patterns and the risk of renal cell carcinoma

  • Kiren Handa (a1) and Nancy Kreiger (a2) (a3)

Abstract

Objectives:

Our objective was to identify food intake patterns that might be associated with the risk of renal cell carcinoma.

Design:

A total of 461 cases (210 females, 251 males) were age frequency matched to population controls. Diet factors were created using factor analysis of 69 food items from a food-frequency questionnaire. These factors were modelled using logistic regression to identify those associated with renal cell carcinoma.

Setting:

We investigated the role of diet in the aetiology of renal cell carcinoma using a population-based case–control study conducted in Ontario between 1995 and 1996.

Subjects:

Cases were Ontario residents 20 to 74 years of age identified through review of pathology reports in the Ontario Cancer Registry.

Results:

A ‘dessert’ diet factor was positively associated with disease for both sexes (odds ratio estimate (OR) for males = 3.7, 95% confidence interval (CI) 2.0–6.9; OR for females = 1.4, 95% CI 0.8–2.2, for the highest vs. lowest quartile). In males, a ‘beef’ diet factor was identified and was associated with an increased risk of renal cell carcinoma. Furthermore, a ‘juices’ diet factor also showed an association with increased risk in males ( OR = 1.8, 95% CI 1.0–3.1). For females, a positive association was observed between renal cell carcinoma and an ‘unhealthy’ diet factor ( OR = 1.4, 95% CI 0.8–2.4).

Conclusions:

Our findings confirmed that high-fat and high-protein diets might be risk factors for renal cell carcinoma. The data also suggest an increased risk associated with juice intake, a finding not previously reported.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Diet patterns and the risk of renal cell carcinoma
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Diet patterns and the risk of renal cell carcinoma
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Diet patterns and the risk of renal cell carcinoma
      Available formats
      ×

Copyright

Corresponding author

*Corresponding author: Email Nancy.Kreiger@cancercare.on.ca

References

Hide All
1Maclure, M, Willett, W. A case–control study of diet and risk of renal adenocarcinoma. Epidemiology 1990; 1: 430–40.
2McLaughlin, J, Mandel, J, Blot, W, et al. A population-based case–control study of renal cell carcinoma. J. Natl. Cancer Inst. 1984; 72: 275–84.
3McLaughlin, J, Gao, Y, Gao, R, et al. Risk factors for renal-cell cancer in Shanghai. China. Int. J. Cancer 1992; 52: 562–5.
4Kreiger, N, Marrett, L, Dodds, L, et al. Risk factors for renal cell carcinoma: results of a population-based case–control study. Cancer Causes Control 1993; 4: 101–10.
5Negri, E, La Vecchia, C, Franceschi, S, et al. Vegetable and fruit consumption and cancer risk. Int. J. Cancer 1991; 48: 350–4.
6Talamini, R, Baron, A, Barra, S, et al. A case–control study of risk factor for renal cell cancer in northern Italy. Cancer Causes Control 1990; 1: 125–31.
7Fraser, G, Phillips, R, Beeson, L. Hypertension, antihypertensive medication and risk of renal carcinoma in California Seventh-Day Adventists. Int. J. Epidemiol. 1990; 19: 832–8.
8Armstrong, B, Doll, R. Environmental factors and cancer incidence and mortality in different countries, with special reference to dietary practices. Int. J. Cancer 1975; 15: 617–31.
9Wynder, E, Mabuchi, K, Whitmore, W. Epidemiology of adenocarcinoma of the kidney. J. Natl. Cancer Inst. 1974; 53: 1619–34.
10Wolk, A, Gridley, G, Niwa, S, et al. International renal cell cancer study. VII. Role of diet. Int. J. Cancer 1996; 65: 6773.
11Wolk, A, Lindblad, P, Adami, H. Nutrition and renal cell cancer. Cancer Causes Control 1996; 7: 518.
12Lindblad, P, Wolk, A, Bergstrom, R, et al. Diet and risk of renal cell cancer: a population-based case–control study. Cancer Epidemiol. Biomark. Prev. 1997; 6: 215–23.
13Chow, W, Gridley, G, McLaughlin, J, et al. Protein intake and risk of renal cell cancer. J. Natl. Cancer Inst. 1994; 86: 1131–9.
14Johnson, K, Mao, Y, Argo, J, et al. The National Enhanced Cancer Surveillance System: a case–control approach to environment-related cancer surveillance in Canada. Environmetrics 1998; 9: 495504.
15World Health Organization (WHO). International Classification of Diseases. Manual of the International Statistical Classification of Diseases, Injuries, and Causes of Death (Nineth Revision). Vol. 1. Geneva: WHO, 1977.
16Villeneuve, P, Johnson, K, Kreiger, N, et al. Risk factors for prostate cancer: results from the Canadian National Enhanced Cancer Surveillance System. Cancer Causes Control 1999; 10: 355–67.
17SAS Institute, Inc., SAS Version 6.12. Cary, NC: SAS Institute, Inc., 1996.
18Breslow, N, Day, N. Statistical Methods in Cancer Research. Vol. I. The Analysis of Case–Control Studies. IARC Scientific Publication No. 32: Lyons, France: International Agency for Research on Cancer (IARC), 1980; 5338.
19Statistics and Epidemiology Research Corporation and Cytel Software Corporation. EGRET®. Seattle, WA: Statistics and Epidemiology Research Corporation and Cytel Software Corporation, 1993.
20McCredie, M, Ford, J, Stewart, J. Risk factors for cancer of the renal parenchyma. Int. J. Cancer 1988; 42: 13–6.
21Prineas, R, Folsom, A, Zhang, Z, et al. Nutrition and other risk factors for renal cell carcinoma in postmenopausal women. Epidemiology 1997; 8: 31–6.
22Benichou, J, Chow, W, McLaughlin, J, et al. Population attributable risk of renal cell cancer in Minnesota. Am. J. Epidemiol. 1998; 148: 424–30.
23Mellemgaard, A, McLaughlin, J, Overvad, K, et al. Dietary risk factors for renal cell carcinoma in Denmark. Eur. J. Cancer 1996; 32A: 673–82.
24Willett, W. Nutritional Epidemiology, 2nd ed. New York: Oxford University Press, 1990.
25Vena, J, Graham, S, Freudenheim, J, et al. Drinking water, fluid intake, and bladder cancer in western New York. Arch. Environ. Health 1993; 48: 191–8.
26Claude, J, Kunse, E, Frentzel-Beyme, R, et al. Life-style and occupational risk factors in cancer of the lower urinary tract. Am. J. Epidemiol. 1986; 124: 578–89.
27Jensen, OM, Wahrendorf, J, Knudsen, JB, et al. The Copenhagen case–control study of bladder cancer II. Effects of coffee and other beverages. Int. J. Cancer 1986; 37: 651–7.
28Michaud, D, Spiegelman, D, Clinton, S, et al. Fluid intake and the risk of bladder cancer in men. N. Engl. J. Med. 1999; 340: 1390–7.
29Pohlabeln, H, Jocket, K, Bolm-Audroff, U. Non-occupational risk factors for cancer of the lower urinary tract in Germany. Eur. J. Epidemiol. 1999; 15: 411–9.
30Slattery, M, Boucher, K, Caan, B, et al. Eating patterns and risk of colon cancer. Am. J. Epidemiol. 1998; 148: 416.
31Slattery, M, Boucher, K. The senior authors' response: factor analysis as a tool for evaluating eating patterns. Am. J. Epidemiol. 1998; 148: 20–1.
32Randall, E, Marshall, J, Graham, S, et al. Patterns in food use and their associations with nutrient intakes. Am. J. Clin. Nutr. 1990; 52: 739–45.
33Byers, T, Marshall, J, Anthony, E, et al. The reliability of dietary history from the distant past. Am. J. Epidemiol. 1987; 125: 9991010.

Keywords

Diet patterns and the risk of renal cell carcinoma

  • Kiren Handa (a1) and Nancy Kreiger (a2) (a3)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed