To the Editor: The paper by Chalder et al. (26, 791–800) in a cross-sectional study concludes that the diagnosis of ‘ME’, which makes an external attribution for fatigue, ‘seems to protect against psychological distress but not against disability’. We should like to offer strong support for this conclusion from the prospective data of a patient involved in a 12-year study of the outcome of neurotic disorder.

To the Editor: A recent Editorial (McGee et al. 26, 441–447) posed the general question ‘Are life events related to the onset of breast cancer?’, but then debated whether or not life events are directly related to the diagnosis of this condition. The distinction is small but vital. On the basis of our own large study (Cooper & Faragher, 1993) we, too, would be reluctant to infer a direct link ; however, we would infer that the occurrence of a major stress event will increase the risk of a breast cancer being detected in some women if other important psychosocial factors are present also.

Applications are invited for awards for research on schizophrenia and bipolar disorder. They may be up to $75000 a year for studies involving human subjects and $50000 a year for other studies. The deadline for applications is 1 March 1997. Further details and application forms can be obtained from: Ms Patrice P. De Haven, Research Awards Coordinator, Stanley Foundation Research Awards Program, c/o NAMI, 200 North Glebe Road, Suite 1015, Arlington VA 22203-3754 USA.