Skip to main content Accessibility help
×
Home

Contents:

Information:

  • Access

Actions:

      • Send article to Kindle

        To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

        Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

        Find out more about the Kindle Personal Document Service.

        The Relationship between Serum Zinc Levels and Myopia (short-sightedness) in Korean Adolescents
        Available formats
        ×

        Send article to Dropbox

        To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

        The Relationship between Serum Zinc Levels and Myopia (short-sightedness) in Korean Adolescents
        Available formats
        ×

        Send article to Google Drive

        To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

        The Relationship between Serum Zinc Levels and Myopia (short-sightedness) in Korean Adolescents
        Available formats
        ×
Export citation

Myopia, or short-sightedness is one of the leading causes of preventable blindness in the world today. Its prevalence has risen drastically over past decades, with no sign of slowing.(1) It has been suggested that low serum zinc levels may contribute to the development of myopia,(2, 3) and therefore, the aim of this present study is to examine the relationship between serum zinc status and myopia, in adolescents, using a large nationally representative dataset.

Data from 304 adolescents aged 12–19 years, who participated in the Korean National Health and Nutrition Examination Study (KNHANES) from 2010 was used in this study. Multivariate logistic regression analysis was performed to examine the relationship between serum zinc status and myopia after adjustment for potential confounders. Additionally, the association between serum zinc and spherical equivalent refractive error (SER) was examined in the myopia group, through multiple linear regression

Among study participants, 84% were found to be myopic (<=−0.5 dioptres [D]). Although mean serum zinc was higher in the non-myopes [139.3 μg/dL] relative to myopes [138.1 μg/dL], the difference was not statistically significant (p = 0.809). In multiple logistic regression analyses, serum zinc was not significantly associated with myopia, after adjustment for age, gender, residence, body mass index (BMI), family income, and recreational activity. In multiple linear regression, SER was not associated with serum zinc in the myopic group, after adjustment for confounding factors (p = 0.629).

In contrast to previous Asian studies, lower serum zinc is not associated with the presence of myopia in Korean adolescents. However, further well-designed prospective studies should be performed in a large cohort of various ethnic groups.

1.Holden, BA, Fricke, TR, Wilson, DA et al. (2016) Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050. Ophthalmology 123(5), 10361042.10.1016/j.ophtha.2016.01.006
2.Fedor, M, Socha, K, Urban, B et al. (2017) Serum Concentration of Zinc, Copper, Selenium, Manganese, and Cu/Zn Ratio in Children and Adolescents with Myopia. Biol Trace Elem Res 176(1), 19.10.1007/s12011-016-0805-1
3.Wang, L (2009) Variation analysis of six kinds of common micro- elements contents of blood in myopic primary school students in Dongguan district. Cent Chin Med J 1, 20–2.10.1186/1749-8546-4-20