Hostname: page-component-848d4c4894-tn8tq Total loading time: 0 Render date: 2024-07-06T06:55:58.409Z Has data issue: false hasContentIssue false
  • English
  • Français

Interleukin-1, interleukin-1 receptor, and interleukin-1 receptor antagonist

Published online by Cambridge University Press:  28 February 2007

N. Joseph Espat ,
Michael A. Rogy ,
Edward M. Copeland  and
Lyle L. Moldawer
N. Joseph Espat
Affiliation:
Department of Surgery, College of Medicine, University of Florida, P.O. Box 100286, Gainsville, Florida 32610-0268, USA
Michael A. Rogy
Affiliation:
Department of Surgery, College of Medicine, University of Florida, P.O. Box 100286, Gainsville, Florida 32610-0268, USA
Edward M. Copeland
Affiliation:
Department of Surgery, College of Medicine, University of Florida, P.O. Box 100286, Gainsville, Florida 32610-0268, USA
Lyle L. Moldawer
Affiliation:
Department of Surgery, College of Medicine, University of Florida, P.O. Box 100286, Gainsville, Florida 32610-0268, USA
Rights & Permissions [Opens in a new window]

Abstract

An abstract is not available for this content so a preview has been provided. As you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
CMNSG Guest Lecture
Information
Proceedings of the Nutrition Society , Volume 53 , Issue 2 , July 1994 , pp. 393 - 400
Copyright
Copyright © The Nutrition Society 1994

References

Arend, W. P. & Dayer, J. M. (1990). Cytokines and cytokine inhibitors or antagonists in rheumatoid arthritis. Arthritis and Rheumatism 33, 305–315.Google Scholar
Arend, W. P., Joslin, F. G. & Massoni, R. J. (1985). Characteristics of chondrocyte responses to a human interleukin 1-like factor. Clinical Immunology and Immunopathology 36, 358–370.CrossRefGoogle ScholarPubMed
Arend, W. P., Welgus, H. G., Thompson, R. C. & Eisenberg, S. P. (1990). Biological properties of recombinant human monocyte derived interleukin 1 receptor antagonist. Journal of Clinical Investigation 85, 1694–1697.Google Scholar
Bertoglio, J. (1988). B-cell derived interleukin-1. CRC Critical Reviews in Immunology 8, 299–313.Google Scholar
Birkhahn, R. H., Long, C. L., Fitkin, D., Geiger, J. W. & Blakemore, W. S. (1980). Effects of major skeletal trauma on whole body protein turnover in man measured by L-[1-14C]leucine. Surgery 88, 294–300.Google Scholar
Carmichael, D. F., Smith, C. G. & Thompson, R. C. (1989). Demonstration of the effect of human interleukin-1 inhibitor in cultured bovine nasal cartilage explant. Cytokine 1, 89.Google Scholar
Castell, J. V., Gomez-Lechon, M. J., David, M., Fabra, R., Trullenque, R. & Heinrich, P. C. (1990). Acute-phase response of human hepatocytes: regulation of acute phase synthesis by interleukin-6. Hepatology 5, 1179–1186.Google Scholar
Chizzonite, R., Truitt, T., Kilian, P. L., Stern, A. S., Nunes, O., Parker, K. P., Kaffka, K. L., Chua, A. O., Lugg, D. K. & Gubler, U. (1989). Two high-affinity interleukin 1 receptors represent separate gene products. Proceedings of the National Academy of Sciences, USA 86, 8029–8033.Google Scholar
Cominelli, F., Nast, C. C., Clark, B. D., Schindler, R., Llerena, R., Eysselein, V. E., Thompson, R. C. & Dinarello, C. A. (1990). Interleukin-1 gene expression, synthesis, and effect of specific IL-1 receptor blockade in rabbit immune complex colitis. Journal of Clinical Investigation 86, 972–980.CrossRefGoogle ScholarPubMed
Cozzolino, F., Torcia, M., Bettoni, S., Aldinucci, D., Burgio, V. L., Petti, M. C., Rubartelli, A., Barbui, T. & Rambaldi, A. (1990). Interleukin-1 and interleukin-2 control granulocyte- and granulocyte-macrophage colony-stimulating factor gene expression and cell proliferation in cultured acute myeloblastic leukemia. International Journal of Cancer 46, 902–908.Google Scholar
Dejana, E., Brevario, F. & Erroi, A. (1987). Modulation of endothelial cell function by different molecular species of interleukin-1. Blood 69, 696–699.Google Scholar
Dinarello, C. A. (1988). Biology of interleukin 1. FASEB Journal 2, 108–115.CrossRefGoogle ScholarPubMed
Dinarello, C. A. (1991). Interleukin-1 and interleukin-1 antagonism. Blood 8, 1627–1652.Google Scholar
Dinarrello, C. A., Cannon, J. G., Berheim, H. A., LoPresti, G., Love, R. & Webb, A. C. (1986 a). Multiple biologic properties of recombinant human interleukin-1. Journal of Clinical Investigation 77, 1734–1739.Google Scholar
Dinarrello, C. A., Cannon, J. G. & Mier, J. W. (1986 b). Multiple biological activities of human recombinant interleukin-1. Journal of Clinical Investigation 77, 1734–1739.Google Scholar
Dinarello, C. A. & Endres, S. (1989). Role for interleukin-1 in the pathogenesis of hypersensitivity diseases. Journal of Cellular Biochemistry 39, 229–238.CrossRefGoogle ScholarPubMed
Dinarello, C. A., Ikejima, T., Warner, S. J. C., Orencole, S. R., Lonnemann, G. & Libby, P. L. (1987). Interleukin-1 induces interleukin-1. I. Induction of circulating interleukin-1 in rabbits in vivo and in human mononuclear cells in vitro . Journal of Immunology 139, 1902–1910.Google Scholar
Dower, S. K., Sims, J. E., Ceretti, D. P. & Bird, T. A. (1992). The interleukin I system: receptors, ligands and signals. In Interleukins: Molecular Biology and Immunology, vol. 51, pp. 33–64 [T., Kishimoto, editor]. Basel: Karger.Google Scholar
Duthie, R. B. & Hoaglund, F. T. (1989). Orthopaedics. In Principles of Surgery, 5th ed., pp. 1987–1992 [Schwartz, S. I. Shires, G. T. and Spencer, F. C., editors]. New York: McGraw Hill.Google Scholar
Eisenberg, S. P., Evans, R. J., Arend, W. P., Verderber, E., Brewer, M. T., Hannum, C. H. & Thompson, R. C. (1990). Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature 343, 341–346.CrossRefGoogle ScholarPubMed
Endres, J., Van Der Meer, W. M. & Dinarello, C. A. (1987). Interleukin-1 in the pathogenesis of fever. European Journal of Clinical Investigation 17, 469–474.Google Scholar
Esser, R. E., Stimpson, S. A., Cromartie, W. J. & Schwab, J. H. (1985). Reactivation of streptococcal cell wall-induced arthritis by homologous and heterologous cell wall polymers. Arthritis and Rheumatism 12, 1402–1411.Google Scholar
Fong, Y., Moldawer, L. L., Marano, M., Manougue, K., Tracey, J. J., Wei, H., Kuo, G., Fischman, D. A., Cerami, A. & Lowry, S. F. (1989). Chronic cachectin or IL-1 administration induces cachexia with redistribution of body proteins. American Journal of Physiology 256, R659–R665.Google Scholar
Fong, Y., Moldawer, L. L., Shires, G. T. & Lowry, S. F. (1990). The biology of cytokines: implications in surgical injury. Surgery in Gynecology and Obstetrics 170, 363–378.Google Scholar
Geiger, T., Andus, T., Klapproth, J., Hirani, T., Kisihimoto, T. & Heinrich, P. C. (1988). Induction of acute-phase proteins by interleukin 6 in vivo. European Journal of Immunology 18, 717–721.Google Scholar
Gershenwald, J. E., Fong, Y., Fahey, T. J. III, Calvano, S. E., Chizzonite, R., Kilian, P. L., Lowry, S. F. & Moldawer, L. L. (1990). Interleukin-1 receptor blockade attenuates the host inflammatory response. Proceedings of the National Academy of Sciences, USA 87, 4966–4970.Google Scholar
Goldberg, A. L., Kettlehut, I. C., Furuno, K., Fagan, J. M. & Baracos, V. M. (1988). Activation of protein breakdown and prostaglandin E2 production in rat skeletal muscle in fever is signalled by a macrophage product distinct from interleukin 1 and other known cytokines. Journal of Clinical Investigation 81, 1378–1381.Google Scholar
Goldberg, S. M., Nivatvongs, S. & Rothenberger, D. A. (1989). Colon, rectum and anus. In Principles of Surgery, 5th ed., pp. 1237–1244 [Schwartz, S. I. Shires, G. T. and Spencer, F. C., editors]. New York: McGraw Hill.Google Scholar
Gubler, U., Chua, A. O. & Stern, A. S. (1986). Recombinant human interleukin-1-alpha: purification and biological characterization. Journal of Immunology 136, 2492–2497.Google Scholar
Harris, E. D. Jr (1988). Pathogenesis of rheumatoid arthritis: A disorder associated with dysfunctional immunoregulation. In Inflammation: Basic Principles and Clinical Correlates, pp. 751–773 [Gallin, J. I. Goldstein, I. M. and Snyderman, R., editors]. New York: Raven Press.Google Scholar
Harris, E. D. Jr (1990). Rheumatoid arthritis: Pathophysiology and implications for therapy. New England Journal of Medicine 322, 1277–1289.Google Scholar
Lang, R. A. & Burgess, A. W. (1990). Autocrine growth factors and tumourogenic transformation. Immunology Today 11, 244–252.Google Scholar
Last-Barnet, K., Homon, C. A. & Feanes, R. B. (1988). Synergistic and overlapping activities of tumor necrosis-alpha and IL-1. Journal of Immunology 141, 527–530.CrossRefGoogle Scholar
Lumpkin, M. D. (1987). The regulation of ACTH secretion by IL-1. Science 238, 452–454.Google Scholar
Mannel, D. N., Moore, R. N. & Mersenberger, S. E. (1980). Macrophages as a source of tumorcidal activity. Infection and Immunity 30, 523–528.Google Scholar
Moissec, P. (1987). The role of interleukin-1 in the pathogenesis of rheumatoid arthritis. Clinical and Experimental Rheumatology 5, 305–308.Google Scholar
Moldawer, L. L. (1991). The beneficial role of cytokines, particularly interleukin-1, in the host response to injury, infection and inflammation. In Cytokines in Biology [Remick, D. G., editor]. New York: McGraw Hill.Google Scholar
Moldawer, L. L. (1992). Interleukin-1 receptor blockade improves survival and hemodynamic performance in E. coli septic shock, but fails to alter host responses to sublethal endotoxemia. Journal of Clinical Investigation 89, 1551–1557.Google Scholar
Moldawer, L. L., Svaninger, G., Gelin, J. & Lundholm, K. G. (1987). Interleukin-1 and tumor necrosis factor do not regulate protein balance in skeletal muscle. American Journal of Physiology C766.Google Scholar
Mule, J. J. & Rosenberg, S. A. (1992). Catalogue of cytokines: Biologic therapy of cancer updates. 1, 1–11.Google Scholar
Nachman, R. L., Hajjar, K. A., Silverstein, R. L. & Dinarello, C. A. (1986). Interleukin-1 induces endothelial cell synthesis of plasminogen activator inhibitor. Journal of Experimental Medicine 163, 1595–1600.Google Scholar
Rambaldi, A., Torcia, M., Bettoni, S., Vannier, E., Burbui, T., Shaw, A. R., Dinarello, C. A. & Cozzolino, F. (1991). Modulation of cell proliferation and cytokine production in acute myeloblastic leukemia by interleukin-1 receptor antagonist and lack of its expression by leukemic cells. Blood 78, 3248–3253.Google Scholar
Rodriguez-Cimadevilla, J. C., Beauchemin, V., Villeneuve, L., Letendre, F., Shaw, A. & Hoang, T. (1990). Coordinate secretion of interleukin-1β and granulocyte-macrophage colony-stimulating factor by the blast cells of acute myeloblastic leukemia: Role of interleukin-1 as an endogenous inducer. Blood 76, 1481–1487.Google Scholar
Rossi, V., Breviario, F., Ghezzi, P., Dejana, E. & Mantovani, A. (1985). Interleukin-1 induces prostacylin in vascular cells. Science 229, 1174–1176.Google Scholar
Schwartz, S. I. (1989). Hemostasis, surgical bleeding and transfusion. In Principles of Surgery, 5th ed., pp. 117–118 [Schwartz, S. I. Shires, G. T. and Spencer, F. C., editors]. New York: McGraw Hill.Google Scholar
Sims, J. E., Gayle, M. A., Slack, J. L., Alderson, M. R., Bird, T. A., Giri, J. D., Colotta, F., Re, F., Mantovani, A., Shanebeck, K., Grabstein, K. H. & Dower, S. K. (1990). Interleukin-1 signaling occurs exclusively via the type 1 receptor. Proceedings of the National Academy of Sciences, USA 90, 6155–6159.CrossRefGoogle Scholar
Thompson, R. C., Dripps, D. J. & Eisenberg, S. P. (1992). Interleukin-1 receptor antagonist (IL-1ra) as a probe and as a treatment for IL-1 mediated disease. International Journal of Immunopharmacology 14, 475–480.Google Scholar
Young, D. C. & Griffin, J. D. (1986). Autocrine secretion of GM-CSF in acute myeloblastic leukemia. Blood 68, 1178–1185.CrossRefGoogle ScholarPubMed
Young, D. C., Wagner, K. & Griffin, J. D. (1987). Constitutive expression of the granulocyte-macrophage colony-stimulating factor gene in acute myeloblastic leukemia. Journal of Clinical Investigation 79, 100–106.Google Scholar