Anderson, H. R. and Fairweather, I. (1995). Fasciola hepatica: ultrastructural changes to the tegument of juvenile flukes following incubation in vitro with the deacetylated (amine) metabolite of diamphenethide. International Journal for Parasitology 25, 319–333.
Buchanan, J. F., Fairweather, I., Brennan, G., Trudgett, A. and Hoey, E. M. (2003). Fasciola hepatica: surface and internal tegumental changes induced by treatment in vitro with the sulphoxide metabolite of albendazole (‘Valbazen’). Parasitology 126, 141–153.
Carr, A. W., McCracken, R. O. and Stillwell, W. H. (1993). Uncoupling of rat liver mitochondria oxidative phosphorylation by the fasciolicide triclabendazole and its sulfoxide and sulfone metabolites. Journal of Parasitology 79, 198–204.
Fairweather, I. and Boray, J. C. (1999). Fasciolicides: efficacy, actions, resistance and its management. Veterinary Journal 158, 81–112.
Fairweather, I., Holmes, S. D. and Threadgold, L. T. (1984). Fasciola hepatica: motility response to fasciolicides in vitro. Experimental Parasitology 57, 209–224.
Fairweather, I., Anderson, H. R. and Threadgold, L. T. (1986) Fasciola hepatica: tegumental changes induced in vitro by the deacetylated (amine) metabolite of diamphenethide. Experimental Parasitology 62, 336–348.
Fairweather, I., Anderson, H. R. and Baldwin, T. M. A. (1987). Fasciola hepatica: tegumental surface alterations following treatment in vitro with the deacetylated (amine) metabolite of diamphenethide. Parasitology Research 73, 99–106.
Fairweather, I., Threadgold, L. T. and Hanna, R. E. B. (1999). Development of Fasciola hepatica in the mammalian host. In Fasciolosis (ed. Dalton, J. P.), pp. 47–111. CAB International Publishing, Oxon, UK.
Halferty, L., Brennan, G. P., Hanna, R. E. B., Edgar, H. W., Meaney, M., McConville, M., Trudgett, A., Hoey, L. and Fairweather, I. (2008). Tegumental surface changes in juvenile Fasciola hepatica in response to treatment in vivo with triclabendazole. Veterinary Parasitology 155, 49–58.
Hanna, R. E. B. (1980). Fasciola hepatica: glycocalyx replacement in the juvenile as a possible mechanism for protection against host immunity. Experimental Parasitology 50, 103–114.
Hernández-Campos, A., Ibarra-Velarde, F., Vera-Montenegro, Y., Rivera-Fernandez, N. and Castillo, R. (2002). Synthesis and fasciolicidal activity of 5-chloro-2-methylthio-6-(1-naphthyloxy)-1H-benzimidazole. Chemical and Pharmaceutical Bulletin 50, 649–652.
Heytler, P. G. (1979). Uncouplers of oxidative phosphorylation. Methods in Enzymology 55, 462–472.
Ibarra, V. F., García, S. E., Fernández, R. M., Vera, M. Y., Castillo, B. R. and Hernández, C. A. (1997 a). Eficacia fasciolicida de dos compuestos de síntesis química in vitro e in vivo en ovinos. Veterinaria México 8, 4–8.
Ibarra, V. F., Vera, M. Y., Hernández, C. A. and Castillo, B. R. (1997 b). Eficacia fasciolicida del compuesto “alfa” contra estadios juveniles y adultos en ovinos. Veterinaria México 28, 297–301.
Ibarra, V. F., Montenegro, C. N., Flores, C. J., Hernández, C. A. and Castillo, B. R. (2000). Evaluación de cuatro vehículos para formular un fasciolicida experimental. Veterinaria México 31, 47–51.
Kelly, R. B. (1990). Microtubules, membrane traffic, and cell organisation. Cell 61, 5–7.
Kumar, D., McGeown, J. G., Reynoso-Ducoing, O., Ambrosio, J. R. and Fairweather, I. (2003). Observations on the musculature and isolated muscle fibres of the liver fluke, Fasciola hepatica. Parasitology 127, 457–473.
McCoy, M. A., Fairweather, I., Brennan, G. P., Kenny, J. M., Ellison, S. and Forbes, A. F. (2005). The efficacy of nitroxynil and triclabendazole administered synchronously against juvenile triclabendazole-resistant Fasciola hepatica in sheep. Research in Veterinary Science 78 (Suppl. A), 33.
McConville, M., Brennan, G. P., McCoy, M., Castillo, R., Hernandez-Campos, A., Ibarra, F. and Fairweather, I. (2006). Adult triclabendazole-resistant Fasciola hepatica: surface and subsurface tegumental responses to in vitro treatment with the sulphoxide metabolite of the experimental fasciolicide compound alpha. Parasitology 133, 195–208.
McConville, M., Brennan, G. P., McCoy, M., Castillo, R., Hernandez-Campos, A., Ibarra, F. and Fairweather, I. (2007). Immature triclabendazole-resistant Fasciola hepatica: tegumental responses to in vitro treatment with the sulphoxide metabolite of the experimental fasciolicide compound alpha. Parasitology Research 100, 365–377.
McConville, M., Brennan, G. P., Flanagan, A., Edgar, H. W. J., McCoy, M., Castillo, R., Hernández-Campos, A. and Fairweather, I. (2008). Surface and internal tegumental changes in juvenile Fasciola hepatica following treatment in vivo with the experimental fasciolicide, compound alpha. Veterinary Parasitology 153, 52–64.
McConville, M., Brennan, G. P., Flanagan, A., Edgar, H. W. J., Hanna, R. E. B., McCoy, M., Gordon, A. W., Castillo, R., Hernández-Campos, A. and Fairweather, I. (2009). An evaluation of the efficacy of compound alpha and triclabendazole against two isolates of Fasciola hepatica. Veterinary Parasitology (in the Press).
McKinstry, B., Fairweather, I., Brennan, G. P. and Forbes, A. B. (2003). Fasciola hepatica: tegumental surface alterations following treatment in vivo and in vitro with nitroxynil (Trodax). Parasitology Research 91, 251–263.
McKinstry, B., Brennan, G. P., Halferty, L., Forbes, A. B. and Fairweather, I. (2007). Ultrastructural changes induced in the tegument and gut of Fasciola hepatica following in vivo and in vitro drug treatment with nitroxynil (Trodax). Parasitology Research 101, 929–941.
McKinstry, B., Halferty, L., Brennan, G. P. and Fairweather, I. (2009). Morphological response of triclabendazole-susceptible and triclabendazole-resistant isolates of Fasciola hepatica to treatment in vitro with nitroxynil (Trodax). Parasitology Research 104, 645–655.
Meaney, M., Fairweather, I., Brennan, G. P., McDowell, L. S. L. and Forbes, A. B. (2003). Fasciola hepatica: effects of the fasciolicide clorsulon in vitro and in vivo on the tegumental surface, and a comparison of the effects on young- and old-mature flukes. Parasitology Research 91, 238–250.
Meaney, M., Fairweather, I., Brennan, G. and Forbes, A. B. (2004). Transmission electron microscope study of the ultrastructural changes induced in the tegument and gut of Fasciola hepatica following treatment with clorsulon. Parasitology Research 92, 232–241.
Meaney, M., Haughey, S., Brennan, G. P. and Fairweather, I. (2005 a). A scanning electron microscope study on the route of entry of clorsulon into the liver fluke, Fasciola hepatica. Parasitology Research 95, 117–128 and 96, 189–198.
Meaney, M., Haughey, S., Brennan, G. P. and Fairweather, I. (2005 b). Ultrastructural observations on oral ingestion and trans-tegumental uptake of clorsulon by the liver fluke, Fasciola hepatica. Parasitology Research 95, 201–212.
Meaney, M., Allister, J., McKinstry, B., McLaughlin, K., Brennan, G. P., Forbes, A. B. and Fairweather, I. (2007). Fasciola hepatica: ultrastructural effects of a combination of triclabendazole and clorsulon against mature fluke. Parasitology Research 100, 1091–1104.
Mottier, L., Alverez, L., Ceballos, L. and Lanusse, C. (2006). Drug transport mechanisms in helminth parasites: passive diffusion of benzimidazole anthelmintics. Experimental Parasitology 113, 49–57.
Ramírez, N., Mayet, L., Del Rivero, L., Ibarra-Velarde, F., Castillo, R., Hernández-Campos, A. and Jung-Cook, H. (2009). Pharmacokinetic behaviour in sheep and cattle of 5-Chloro-2-(methylthio)-6-(1-naphthyloxy)-1H-benzimidazole, a new fasciolicide agent. Journal of Veterinary Pharmacology and Therapeutics (in the Press).
Rivera, F. N., Ibarra, V. F., Olazaràn, J. S., Vera, M. Y., Castillo, B. R. and Hernández, C. A. (2002). Efficacy of 5-chloro-2-methylthio-6-(1-naftiloxi)-ih-benzimidazole against different stages of Fasciola hepatica in Pelibuey sheep. Veterinaria México 33, 55–61.
Rivera, N., Ibarra, F., Zepeda, A., Fortoul, T., Cantó, G., Hernández, A. and Castillo, R. (2005). The effect of the 5-chloro-2-methylthio-6-(1-naphtyloxy)-H-benzimidazole on the tegument of immature Fasciola hepatica in their natural host. Parasitology Research 95, 379–383.
Rivera, N., Ibarra, F., Zepeda, A., Fortoul, T., Hernández, A., Castillo, R. and Cantó, G. (2004). Tegumental surface changes in adult Fasciola hepatica following treatment in vitro and in vivo with an experimental fasciolicide. Parasitology Research 93, 283–286.
Rivero, L. M., Jung, H., Castillo, R. and Hernández Campos, A. (1998). High-performance liquid chromatographic assay for a new fasciolicide agent, α-BIOF10, in biological fluids. Journal of Chromatography B 712, 237–241.
Robinson, G. and Threadgold, L. T. (1975). Electron microscope studies of Fasciola hepatica. XII. The fine structure of the gastrodermis. Experimental Parasitology 37, 20–36.
Robinson, M. W., Trudgett, A., Hoey, E. M. and Fairweather, I. (2002). Triclabendazole-resistant Fasciola hepatica: ß-tubulin and response to in vitro treatment with triclabendazole. Parasitology 124, 325–338.
Robinson, M. W., Trudgett, A., Hoey, E. M. and Fairweather, I. (2003). The effect of the microtubule inhibitor tubulozole-C on the tegument of triclabendazole-susceptible and triclabendazole-resistant Fasciola hepatica. Parasitology Research 91, 117–129.
Skuce, P. J. and Fairweather, I. (1990). The effect of the hydrogen ionophore closantel upon the pharmacology and ultrastructure of the adult liver fluke Fasciola hepatica. Parasitology Research 76, 241–250.
Stitt, A. W. and Fairweather, I. (1993 a). Fasciola hepatica: tegumental surface changes in adult and juvenile flukes following treatment in vitro with the sulphoxide metabolite of triclabendazole (‘Fasinex’). Parasitology Research 79, 529–536.
Stitt, A. W. and Fairweather, I. (1993 b). Fasciola hepatica: the effect of the microtubule inhibitors colchicine and tubulozole-C on the ultrastructure of the adult fluke. Parasitology 107, 297–309.
Stitt, A. W. and Fairweather, I. (1994). The effect of the sulphoxide metabolite of triclabendazole (‘Fasinex’) on the tegument of mature and immature stages of the liver fluke, Fasciola hepatica. Parasitology 108, 555–567.
Threadgold, L. T. and Brennan, G. (1978). Fasciola hepatica: basal infolds and associated vacuoles of the tegument. Experimental Parasitology 46, 300–316.
Toner, E., McConvery, F., Meaney, M., Brennan, G. P. and Fairweather, I. (2009). A scanning electron microscope study on the route of entry of triclabendazole into the liver fluke, Fasciola hepatica. Parasitology 136 (in Press).
Verheyen, A., Vanparijs, O., Lauwers, H. and Thienpont, D. (1980). The influence of closantel administration to sheep on the ultrastructure of the adult liver fluke, Fasciola hepatica L. In The Host-Invader Interplay (ed. Van den Bossche, H.), pp. 705–708. Elsevier/North Holland, Amsterdam, The Netherlands.
Walker, S. M., McKinstry, B., Boray, J. C., Brennan, G. P., Trudgett, A., Hoey, E. M., Fletcher, H. and Fairweather, I. (2004). Response of two isolates of Fasciola hepatica to treatment with triclabendazole in vivo and in vitro. Parasitology Research 94, 427–438.
