Anderson, CF, Lira, R, Kamhawi, S, Belkaid, Y, Wynn, TA and Sacks, D (2008) IL-10 and TGF-beta control the establishment of persistent and transmissible infections produced by Leishmania tropica in C57BL/6 mice. Journal of Immunology 180, 4090–4097.
Atayde, VD, Aslan, H, Townsend, S, Hassani, K, Kamhawi, S and Olivier, M (2015) Exosome secretion by the parasitic protozoan Leishmania within the sand fly midgut. Cell Reports 13, 957–967.
Badirzadeh, A, Taheri, T, Taslimi, Y, Abdossamadi, Z, Heidari-Kharaji, M, Gholami, E, Sedaghat, B, Niyyat, M and Rafati, S (2017) Arginase activity in pathogenic and non-pathogenic species of Leishmania parasites. PLoS Neglected Tropical Diseases 11, e0005774.
Bates, PA (1997) Transmission of Leishmania metacyclic promastigotes by phlebotomine sand flies. International Journal of Parasitology 37, 1097–1106.
Belkaid, Y, Kamhawi, S, Modi, G, Valenzuela, J, Noben-Trauth, N, Rowton, E, Ribeiro, J and Sacks, DL (1998) Development of a natural model of cutaneous leishmaniasis: powerful effects of vector saliva and saliva pre-exposure on the long-term outcome of Leishmania major infection in the mouse ear dermis. Journal of Experimental Medicine 188, 1941–1953.
Dey, R, Joshi, AB, Oliveira, F, Pereira, L, Guimarães-Costa, AB, Serafim, TD, de Castro, W, Coutinho-Abreu, IV, Bhattacharya, P, Townsend, S, Aslan, H, Perkins, A, Karmakar, S, Ismail, N, Karetnick, M, Meneses, C, Duncan, R, Nakhasi, HL, Valenzuela, JG and Kamhawi, S (2018) Gut microbes egested during bites of infected sand flies augment severity of leishmaniasis via inflammasome-derived IL-1β. Cell Host and Microbe 23, 134–143..
Dvorak, V, Shaw, J and Volf, P (2018) Parasite biology: the vectors. In Bruschi, F and Gradoni, L (eds), The Leishmaniases Old Neglected Tropical Diseases. Switzerland: Springer International Publishing AG, pp. 31–77. https://doi.org/10.1007/978-3-319-72386-0.
Gebre-Michael, T, Balkew, M, Ali, A, Ludovisi, A and Gramiccia, M (2004) The isolation of Leishmania tropica and L. aethiopica from Phlebotomus (paraphlebotomus) species (Diptera: Psychodidae) in the Awash Valley, northeastern Ethiopia. Transactions of the Royal Society of Tropical Medicine and Hygiene 98, 64–70.
Giraud, E, Lestinova, T, Derrick, T, Martin, O, Dillon, RJ, Volf, P, Műller, I, Bates, PA and Rogers, ME (2018) Leishmania proteophosphoglycans regurgitated from infected sand flies accelerate dermal wound repair and exacerbate leishmaniasis via insulin-like growth factor 1-dependent signalling. PLoS Pathogens 14, e1006794.
Giraud, E, Martin, O, Yakob, L and Rogers, M (2019) Quantifying Leishmania metacyclic promastigotes from individual sand fly bites reveals the efficiency of vector transmission. Communications Biology 2, 84.
Green, SJ, Meltzer, MS, Hibbs, JB and Nacy, CA Jr (1990) Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanism. Journal of Immunology 144, 278–283.
Ilg, T (2000) Proteophosphoglycans of Leishmania. Trends in Parasitology 16, 489–497.
Ilg, T, Stierhof, YD, Craik, D, Simpson, R, Handman, E and Bacic, A (1996) Purification and structural characterization of a filamentous, mucin-like proteophosphoglycan secreted by Leishmania parasites. Journal of Biological Chemistry 271, 21583–22159.
Jacobson, RL, Eisenberger, CL, Svobodová, M, Baneth, G, Sztern, J, Carvalho, J, Nasereddin, A, El Fari, M, Shalom, U, Volf, P, Votypka, J, Dedet, JP, Pratlong, F, Schonian, G, Schnur, LF, Jaffe, CL and Warburg, A (2003) Outbreak of cutaneous leishmaniasis in northern Israel. Journal of Infectious Diseases 188, 1065–1073.
Kamhawi, S, Belkaid, Y, Modi, G, Rowton, E and Sacks, DL (2000) Protection against cutaneous leishmaniasis resulting from bites of uninfected sandflies. Science 290, 1351–1354.
Kimblin, N, Peters, N, Debrabant, A, Secundino, N, Egen, J, Lawyer, P, Fay, MP, Kamhawi, S and Sacks, D (2008) Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies. Proceedings of the National Academy of Science USA 105, 10125–10130.
Klaus, S and Frankenburg, S (1999) Cutaneous leishmaniasis in the Middle East. Clinical Dermatology 17, 137–141.
Kobets, T, Havelková, H, Grekov, I, Volkova, V, Vojtíšková, J, Slapničková, M, Kurey, I, Sohrabi, Y, Svobodová, M, Demant, P and Lipoldová, M (2012) Genetics of host response to Leishmania tropica in mice – different control of skin pathology, chemokine reaction, and invasion into spleen and liver. PLoS Neglected Tropical Diseases 6, e1667.
Lira, R, Méndez, S, Carrera, L, Jaffe, C, Neva, F and Sacks, D (1998) Leishmania tropica: the identification and purification of metacyclic promastigotes and use in establishing mouse and hamster models of cutaneous and visceral disease. Experimental Parasitology 89, 331–342.
Maroli, M, Feliciangeli, MD, Bichaud, L, Charrel, RN and Gradoni, L (2013) Phlebotomine sandflies and the spreading of leishmaniases and other diseases of public health concern. Medical and Veterinary Entomology 27, 123–147.
Montgomery, J, Curtis, J and Handman, E (2002) Genetic and structural heterogeneity of proteophosphoglycans in Leishmania. Molecular and Biochemical Parasitology 121, 75–85.
Mortazavi, H, Sadeghipour, P, Taslimi, Y, Habibzadeh, S, Zali, F, Zahedifard, F, Rahmati, J, Kamyab, K, Ghandi, N, Zamanian, A, Reza Tohidinik, H, Muller, I, Kropf, P and Rafati, S (2016) Comparing acute and chronic human cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica focusing on arginase activity. Journal of the European Academy of Dermatology and Venereology 30, 2118–2121.
Myskova, J, Svobodova, M, Beverley, SM and Volf, P (2007) A lipophosphoglycan-independent development of Leishmania in permissive sand flies. Microbes and Infection 9, 317–324.
Noben-Trauth, N, Kropf, P and Müller, I (1996) Susceptibility to Leishmania major infection in interleukin-4-deficient mice. Science 271, 987–990.
Rath, M, Müller, I, Kropf, P, Closs, EI and Munder, M (2014) Metabolism via arginase or nitric oxide synthase: two competing arginine pathways in macrophages. Frontiers in Immunology 532, 10.
Rogers, ME (2012) The role of Leishmania proteophosphoglycans in sand fly transmission and infection of the mammalian host. Frontiers in Microbiology 223, 13.
Rogers, ME and Bates, PA (2007) Leishmania manipulation of sand fly feeding behavior results in enhanced transmission. PLoS Pathogens 3, e91.
Rogers, ME, Chance, ML and Bates, PA (2002) The role of promastigote secretory gel in the origin and transmission of the infective stage of Leishmania mexicana by the sandfly Lutzomyia longipalpis. Parasitology 124, 495–507.
Rogers, ME, Ilg, T, Nikolaev, AV, Ferguson, MA and Bates, PA (2004) Transmission of cutaneous leishmaniasis by sand flies is enhanced by regurgitation of fPPG. Nature 430, 463–467.
Rogers, M, Kropf, P, Choi, BS, Dillon, R, Podinovskaia, M, Bates, P and Müller, I (2009) Proteophosphoglycans regurgitated by Leishmania-infected sand flies target the L-arginine metabolism of host macrophages to promote parasite survival. PLoS Pathogens 5, e1000555.
Rogers, ME, Corware, K, Müller, I and Bates, PA (2010) Leishmania infantum proteophosphoglycans regurgitated by the bite of its natural sand fly vector, Lutzomyia longipalpis, promote parasite establishment in mouse skin and skin-distant tissues. Microbes and Infection 12, 875–879.
Serafim, TD, Dey, R, Nakhasi, HL, Valunzuela, JG and Kamhawi, S (2017) Unique features of vector-transmitted leishmaniasis and their relevance to disease transmission and control. In Wikel, SK, Aksoy, S and Dimopoulos, G (eds), Arthropod Vector: Controller of Disease Transmission, Volume 2. Vector Saliva-Host-Pathogen Interactions. United States of America: Academic Press, pp. 91–114.
Shortt, HE and Swaminath, CS (1928) The method of feeding of Phlebotomus argentipes with relation to its bearing on the transmission of kala-azar. Indian Journal of Medical Research 15, 827–836.
Stierhof, YD, Bates, PA, Jacobson, RL, Rogers, ME, Schlein, Y, Handman, E and Ilg, T (1999) Filamentous proteophosphoglycan secreted by Leishmania promastigotes forms gel-like three-dimensional networks that obstruct the digestive tract of infected sandfly vectors. European Journal of Cellular Biology 78, 675–689.
Svobodová, M, Votýpka, J, Nicolas, L and Volf, P (2003) Leishmania tropica in the black rat (Rattus rattus): persistence and transmission from asymptomatic host to sand fly vector Phlebotomus sergenti. Microbes and Infection 5, 361–364.
Svobodová, M, Volf, P and Votýpka, J (2006a) Experimental transmission of Leishmania tropica to hyraxes (Procavia capensis) by the bite of Phlebotomus arabicus. Microbes and Infection 8, 1691–1694.
Svobodova, M, Votypka, J, Peckova, J, Dvorak, V, Nasereddin, A, Baneth, G, Sztern, J, Kravchenko, V, Orr, A, Meir, D, Schnur, LF, Volf, P and Warburg, A (2006b) Distinct transmission cycles of Leishmania tropica in 2 adjacent foci, Northern Israel. Emerging Infectious Diseases 12, 1860–1868.
Titus, RG and Ribeiro, JM (1988) Salivary gland lysates from the sand fly Lutzomyia longipalpis enhance Leishmania infectivity. Science 239, 1306–1308.
Volf, P and Myskova, J (2007) Sand flies and Leishmania: specific versus permissive vectors. Trends in Parasitology 23, 91–92.
Volfova, V, Hostomska, J, Cerny, M, Votypka, J and Volf, P (2008) Hyaluronidase of bloodsucking insects and its enhancing effect on Leishmania infection in mice. PLoS Neglected Tropical Diseases 2, e294.