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Physiology and pharmacology of turbellarian neuromuscular systems

Published online by Cambridge University Press:  06 April 2009

K. L. Blair  and
P. A. V. Anderson
K. L. Blair
Affiliation:
Whitney Laboratory, University of Florida, 9505 Ocean Shore Blvd., St. Augustine, FL 32086, USA Department of Biological Sciences and Center for Research in Environmental Signal Transduction, University of Western Michigan, Kalamazoo, MI 49008, USA
P. A. V. Anderson
Affiliation:
Whitney Laboratory, University of Florida, 9505 Ocean Shore Blvd., St. Augustine, FL 32086, USA
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Summary

Our understanding of the neurobiology of the Platyhelminthes has come in large part from free-living turbellarians. In addition to providing considerable information about the capabilities of the rudimentary nervous system present in all members of the phylum, turbellarians have provided the most definitive information about the variety of ion channels present in the membranes of neurones and muscle cells, and about the physiology and pharmacology of those channels. Furthermore, preparations of single, viable muscle cells have provided some of the most conclusive evidence about the variety of transmitters present, and the types of response they evoke. Here, we review what is known about the physiology and pharmacology of the turbellarian neuromuscular system. Particular attention is given to the triclad flatworm Bdelloura Candida, the best studied species in this respect, but other species are included where relevant.

Keywords

Electrophysiologysodium currentscalcium currentspotassium currentsmuscle cellsneurotransmittersion channels
Type
Research Article
Information
Parasitology , Volume 113 , supplement S1: Molecular biochemistry and physiology of helminth neuromuscular systems , January 1996 , pp. S73 - S82
Copyright
Copyright © Cambridge University Press 1996

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