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Novel anti-malarial hydroxynaphthoquinones with potent broad spectrum anti-protozoal activity

  • A. T. Hudson (a1), A. W. Randall (a1), M. Fry (a2), C. D. Ginger (a2), B. Hill (a2), V. S. Latter (a2), N. McHardy (a2) and R. B. Williams (a3)...

Extract

Novel hydroxynaphthoquinones are reported with outstanding efficacy against Plasmodium, Eimeria and Theileria species. Biochemical evidence is presented for the selective toxicity of these compounds being due to inhibition of parasite respiratory systems.

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Novel anti-malarial hydroxynaphthoquinones with potent broad spectrum anti-protozoal activity

  • A. T. Hudson (a1), A. W. Randall (a1), M. Fry (a2), C. D. Ginger (a2), B. Hill (a2), V. S. Latter (a2), N. McHardy (a2) and R. B. Williams (a3)...

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