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Mycoses, bacterial infections and antibacterial activity in sandifies (Psychodidae) and their possible role in the transmission of leishmaniasis

  • Y. Schlein (a1), I. Polacheck (a2) and B. Yuval (a1)


High incidence of mycoses were found in the guts and malpighian tubes of Phlebokomus papatasi from the Jordan Valley and P. tobbi from Zakinthos, Greece. Infections with several different bacteria were also found in the guts of female P. tobbi. Fungi cultured from guts of laboratory reared P. papatasi that had similar mycoses were identified as Aspergillus scierotiorum and Saccharomyces cerevisiae. Fungi-infected laboratory reared P. papatasi were refractory to artificial infections with a Leishmania major strain specific to them. The crop contents of P. papatasi, where sugar meals are stored, demonstrated antibacterial activity against the following bacterial species in culture: Escherichia coli, Staphylococcus aureus, Shigella sonnei, Streptococcus group A and Pseudomonas aeruginosa. It is postulated that the bacteria-free gut normal to sandflies is effected by the bacterial inhibitor present in the crop.



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Adler, S. (1964). Leishmania. Advances in Parasitology 2, 3596.
Adler, S. & Theodor, O. (1927). The transmission of Leishmania tropica from artificially infected sandflies to man. Annals of Tropical Medicine and Parasitology 21, 89110.
Adler, S. & Theodor, O. (1929). Attempts to transmit Leishmania tropica by bite: The transmission of L. tropica by Phlebotomus sergenti. Annals of Tropical Medicine and Parasitology 23, 118.
Chapman, R. F. (1982). The Insects Structure and Function. London, Sydney, Auckland, Toronto: Hodder and Stoughton.
Emmons, C. E., Binpord, C. H., Utz, J. P. & Kwon Chung, K. J. (1977). Medical Mycology. Philadelphia: Lea Febiger.
Friend, W. G. & Smith, J. J. B. (1977). Factors affecting feeding by blood-sucking insects. Annual Review of Entomology 22, 309–31.
Hultmark, D., Engstrom, A., Bennich, H., Kapur, R. & Boman, H. G. (1982). Insect immunity: isolation and structure of cecropin D and four minor antibacterial components from Cecropia pupae. European Journal of Biochemistry 127, 207–17.
Jobling, B. (1976). On the fascicle of blood-sucking Diptera. In addition a description of the maxillary glands in Phlebotomus Papatasi, together with the musculature of the labrum and pulsatory organ of both the latter species and also of some other Diptera. Journal of Natural History 10, 457–61.
Killick-Kendrick, R. (1979). Biology of Leishmania in phlebotomine sandflies. In Biology of Kinetoplastida, vol. 2 (ed. Lumsden, W. H. R. and Evans, D. A.), pp. 395449. London and New York: Academic Press.
Krantz, G. W. (1975). A Manual of Acarology. Corvallis Oregon: O.S.U. Book Stores.
Madelin, M. F. (1963). Diseases caused by Hyphomycetes fungi. In Insect Pathology and Advanced Treatise, vol. 2, (ed. Steinhaus, E. A.), pp. 234271. New York: Academic Press.
Madelin, M. F. (1968). Fungal parasites of invertebrates. In The Fungi and Advanced Treatise (ed. Ainsworth, G. C. and Sussman, A. S.), pp. 227–38. New York and London: Academic Press.
Okada, M. & Natory, S. (1983). Purification and characterization of an antibacterial protein from the haemolymph of Sarcophaga peregrina (flesh-fly) larvae. Biochemistry Journal 211, 727–34.
Raper, K. B. & Fennel, D. I. (1977). The Genus Aspergillus. Huntington New York: Robert F. Krieger.
Schaerffenberg, B. (1957). Infektions um Entwicklungsverlauf des Insektentötenden Pilzes Beauveria bassiana (Vuill) Link. Zeitschrift für angewandte Entomologie 41, 395402.
Schlein, Y., Warburg, A., Schnue, L. F. & Gunners, A. E. (1982). Leishmaniasis in the Jordan Valley II. Sandflies and transmission in the central endemic area. Transactions of the Royal Society of Tropical Medicine and Hygiene 76, 582–6.
Schlein, Y., Warburg, A., Schnur, L. F. & Schlomai, J. (1983). Vector compatibility of Phlebotomus papatasi dependent on differentially induced digestion. Acta Tropica 40, 6770.
Silva-Hunter, M. & Cooper, B. H. (1980). Yeasts of medical importance. In Manual of Clinical Microbiology (ed. Lennette, E. H., Ballows, A., Haustler, W. J. Jr. and Truant, J. P.), pp. 562–76. Washington D. C.: American Society of Microbiology.
Speare, A. T. (1920). Further studies on Soropsorella uvella a fungus parasite of noctuid larvae. Journal of Agriculture Research 18, 399440.
Steiner, H., Hultmark, D., Engstrom, A., Bennich, H. & Boman, H. G. (1981). Sequence and specificity of two antibacterial proteins involved in insect immunity. Nature, London 292, 246–8.
Willers, D., Lehman-Danziger, H. & Führer, E. (1982). Antibacterial and antimycotic effect of newly discovered secretion from larvae of an endoparasitic insect, Pimla turionella L. (Hym). Archives of Microbiology 133, 255–9.
Young, D. G. & Lewis, D. J. (1980). Pathogens of Psychodidae (phlebotomine sandflies). In Bibliography on Pathogens of Medically Important Arthropods (ed. Roberts, D. W. and Castillo, J. M.), pp. 912. Suppl. to Vol. 58 Bulletin of the World Health Organization. Geneva: World Health Organization.

Mycoses, bacterial infections and antibacterial activity in sandifies (Psychodidae) and their possible role in the transmission of leishmaniasis

  • Y. Schlein (a1), I. Polacheck (a2) and B. Yuval (a1)


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