Hostname: page-component-77c89778f8-sh8wx Total loading time: 0 Render date: 2024-07-17T18:34:16.066Z Has data issue: false hasContentIssue false
  • English
  • Français

Immunity to malaria and piroplasmosis in mice following low level infections with Anthemosoma garnhami (Piroplasmea: Dactylosomidae)

Published online by Cambridge University Press:  06 April 2009

F. E. G. Cox
F. E. G. Cox
Affiliation:
Department of Zoology, University of London King's College, Strand, London WC2R 2LS
Get access Rights & Permissions [Opens in a new window]

Extract

Mice which have recovered from infections with A. garnhami do not succumb to; challenge with the piroplasms B. rodhaini or B. microti and over half such animals are protected against the malaria parasites P. v. vinckei and P. v. chabaudi. This protection does not extend to the malaria parasites P. b. berghei or P. b. yoelii. Mice which have recovered from infections with the piroplasms are protected against A. garnhami, as are those which have recovered from infections with P. v. vinckei or P. v. chabaudi. About half the mice which have recovered from infections with P. b. berghei or P. b. yoelii are also protected against A. garnhami. This interaction between intra-erythrocytic protozoa may influence the incidence of these parasites in the wild. A. garnhami is unlikely to be of any use in the immunization of humans against malaria but could be of use in the protection of cattle against piroplasmosis.

Type
Research Article
Information
Parasitology , Volume 65 , Issue 3 , December 1972 , pp. 389 - 398
Copyright
Copyright © Cambridge University Press 1972

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Cox, F. E. G. (1970). Protective immunity between malaria parasites and piroplasms in mice. Bulletin of the World Health Organization 43, 325–36.Google ScholarPubMed
Cox, F. E. G. (1972). Protective heterologous immunity between Plasmodium atheruri and other Plasmodium spp. and Babesia spp. in mice. Parasitology 65, 379–87.CrossRefGoogle ScholarPubMed
Cox, F. E. G. & Voller, A. (1966). Cross-immunity between the malaria parasites of rodents. Annals of Tropical Medicine and Parasitology 60, 297–303.CrossRefGoogle ScholarPubMed
Cox, F. E. G. & Young, A. S. (1969). Acquired immunity to Babesia microti and Babesia rodhaini in mice. Parasitology 59, 257–68.CrossRefGoogle ScholarPubMed
Killick-Kendrick, R. (1971). The collection of strains of murine malaria parasites in the field, and their maintenance in the laboratory by cyclical passage. Symposia of the British Society for Parasitology 9, 39–64.Google Scholar
Landau, I., Boulard, Y. & Houin, R. (1969). Anthemosoma garnhami n. g. n.sp., premier Dactylosomidae connu chez un mammifère. Compte rendu hebdomadaire des séances de l' Académic des sciences 268, 873–5.Google Scholar
Vivier, E. & Petitprez, A. (1969). Observations ultrastructurales sur l'hematozoaire Anthemosoma garnhami et examen des criteres morphologiques utilisables pour la taxonomie chez les sporozoaires. Protistologica 5, 363–79.Google Scholar
Voller, A. (1964). Fluorescent antibody methods and their use in malaria research. Bulletin of the World Health Organization 30, 343–54.Google ScholarPubMed