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Epidemiological and molecular evidence supports the zoonotic transmission of Giardia among humans and dogs living in the same community

  • R. J. TRAUB (a1), P. T. MONIS (a2), I. ROBERTSON (a1), P. IRWIN (a1), N. MENCKE (a3) and R. C. A. THOMPSON (a1)...


Giardia duodenalis isolates recovered from humans and dogs living in the same locality in a remote tea-growing community of northeast India were characterized at 3 different loci; the SSU-rDNA, elongation factor 1-alpha (ef1-α) and triose phosphate isomerase (tpi) gene. Phylogenetic analysis of the SSU-rDNA and ef1-α genes provided poor genetic resolution of the isolates within various assemblages, stressing the importance of using multiple loci when inferring genotypes to Giardia. Analysis of the tpi gene provided better genetic resolution and placed canine Giardia isolates within the genetic groupings of human isolates (Assemblages A and B). Further evidence for zoonotic transmission was supported by epidemiological data showing a highly significant association between the prevalence of Giardia in humans and presence of a Giardia-positive dog in the same household (odds ratio 3·01, 95% CI, 1·11, 8·39, P=0·0000).


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WHO Collaborating Centre for the Molecular Epidemiology of Parasitic Infections, School of Veterinary and Biomedical Sciences, Murdoch University, South Street, Murdoch, Western Australia 6150. Tel: +61 (08) 93602466. Fax: +61 (08) 93104144. E-mail:


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Epidemiological and molecular evidence supports the zoonotic transmission of Giardia among humans and dogs living in the same community

  • R. J. TRAUB (a1), P. T. MONIS (a2), I. ROBERTSON (a1), P. IRWIN (a1), N. MENCKE (a3) and R. C. A. THOMPSON (a1)...


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