Skip to main content Accessibility help
×
Home

Consequences of reduced umbilical and increased fœtal cerebral flow during malaria crisis on fœtal behaviour

  • P. ARBEILLE (a1), G. CARLES (a2), M. GEORGESCU (a1), N. TOBAL (a1), S. HERAULT (a1), F. BOUSQUET (a2) and F. PERROTIN (a1)...

Abstract

The objectives of this study were (a) to evaluate the sensitivity and specificity of fœtal Doppler indices for the prediction of abnormal fœtal heart rate (aFHR) at delivery after malaria crisis and (b) to test Doppler parameters against crisis duration for predicting aFHR. Every day during the malaria crisis, the umbilical and cerebral vascular resistance indices were measured by Doppler. These indices allowed evaluation of the amplitude of the fœtal flow redistribution induced by malaria (C/U=cerebral resistance/umbilical resistance ratio), the duration of the flow redistribution period and the hypoxic index (mean %C/U change×crisis duration). It was found that the mean duration of the flow redistribution period was: 7±2 days, mean C/U change −7%±4, hypoxic index −56±37, prematures 35%, and aFHR 17%. An hypoxic index >150 predicted occurrence of aFHR with high sensitivity and specificity (100%/91%). The highest fœtal flow disturbance (max %C/U) and the duration of the period with flow disturbance (>7 days) predicted aFHR at delivery with a sensitivity of 10% and 40% and a specificity of 77% and 78%. It was concluded that the hypoxic index was more predictive of aFHR at delivery than the amplitude or the duration (i.e. crisis duration) of the fœtal flow redistribution.

Copyright

Corresponding author

Département Medecine Nucléaire et Ultrasons, INSERM 316 – Chu Trousseau, 37044 Tours, France. Tel: +33 2 47 47 59 39. Fax: +33 2 47 47 59 13. E-mail: arbeille@med.univ-tours.fr

Keywords

Consequences of reduced umbilical and increased fœtal cerebral flow during malaria crisis on fœtal behaviour

  • P. ARBEILLE (a1), G. CARLES (a2), M. GEORGESCU (a1), N. TOBAL (a1), S. HERAULT (a1), F. BOUSQUET (a2) and F. PERROTIN (a1)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed