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Biological controls in mixed trichostrongyle infections

Published online by Cambridge University Press:  06 April 2009

J. H. Whitlock  and
J. R. Georgi
J. H. Whitlock
Affiliation:
Department of Pathology, New York State Veterinary College, Cornell University, Ithaca, N.Y. 14853
J. R. Georgi
Affiliation:
Department of Pathology, New York State Veterinary College, Cornell University, Ithaca, N.Y. 14853
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Summary

The parasite reaction phenotype of 80 lambs was determined with natural infection on pasture. These lambs were then assigned to outcome groups and randomized into treatment groups. Developing some simple but unusual analytical techniques it was possible to demonstrate that mixed natural infections of trichostrongyles with the chief biomass component Haemonchus contortus cayugensis protected against superinfections with 35000 infective larvae but protected against superinfections with 1000 infective larvae per day only within the limits characteristic of the enclosing barn ecosystem. The limits of the barn ecosystem were less constraining on more diathetic sheep than the natural pasture infection. Internal evidence from the experiment suggests that the interaction of sheep × pasture × infective trichostrongylid larvae constrains the parasite biomass in the host in more diathetic animals at significantly lower levels. Anaphylactoid ‘self-cure’ did not occur in this experiment but something like premunition certainly did.

Type
Research Article
Information
Parasitology , Volume 72 , Issue 3 , June 1976 , pp. 207 - 224
Copyright
Copyright © Cambridge University Press 1976

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