Skip to main content Accessibility help
×
Home

Antigenic variability in Trichuris trichiura populations

  • R. M. CURRIE (a1), C. S. NEEDHAM (a1), L. J. DRAKE (a1), E. S. COOPER (a2) and D. A. P. BUNDY (a1)...

Abstract

The present study examines antigenic variability for the human whipworm Trichuris trichiura. Recognition by IgG of somatic antigens of individual worms collected from 3 intensely infected children from Jamaica, West Indies has been investigated by immunoblotting. When probed with 1 plasma sample, significant differences in recognition of 2 selected antigens among worm populations and between male and female worms was observed. In addition, there was evidence for antigenic variability within worm populations at the individual worm level. Such variation may have considerable implications for the development of immunity to parasitic nematodes.

Copyright

Corresponding author

Corresponding author: The Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK. Tel: +01865 281229. Fax: +01865 281245. E-mail: rachel.currie@zoology.oxford.ac.uk

Keywords

Antigenic variability in Trichuris trichiura populations

  • R. M. CURRIE (a1), C. S. NEEDHAM (a1), L. J. DRAKE (a1), E. S. COOPER (a2) and D. A. P. BUNDY (a1)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed