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An overview on Leishmania (Mundinia) enriettii: biology, immunopathology, LRV and extracellular vesicles during the host–parasite interaction

  • Larissa F. Paranaiba (a1), Lucélia J. Pinheiro (a2), Diego H. Macedo (a3), Armando Menezes-Neto (a3), Ana C. Torrecilhas (a4), Wagner L. Tafuri (a2) and Rodrigo P. Soares (a3)...

Abstract

One of the Leishmania species known to be non-infective to humans is Leishmania (Mundinia) enriettii whose vertebrate host is the guinea pig Cavia porcellus. It is a good model for cutaneous leishmaniasis, chemotherapeutic and molecular studies. In the last years, an increased interest has emerged concerning the L. (Mundinia) subgenus after the finding of Leishmania (M.) macropodum in Australia and with the description of other new/putative species such as L. (M.) martiniquensis and ‘L. (M.) siamensis’. This review focused on histopathology, glycoconjugates and innate immunity. The presence of Leishmania RNA virus and shedding of extracellular vesicles by the parasite were also evaluated.

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Corresponding author

Author for correspondence: Rodrigo P. Soares, E-mail: rsoares@cpqrr.fiocruz.br

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These authors contributed equally to this work.

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References

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Keywords

An overview on Leishmania (Mundinia) enriettii: biology, immunopathology, LRV and extracellular vesicles during the host–parasite interaction

  • Larissa F. Paranaiba (a1), Lucélia J. Pinheiro (a2), Diego H. Macedo (a3), Armando Menezes-Neto (a3), Ana C. Torrecilhas (a4), Wagner L. Tafuri (a2) and Rodrigo P. Soares (a3)...

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