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Chick embryo infections for the evaluation of anticoccidial drugs

Published online by Cambridge University Press:  06 April 2009

J. F. Ryley
J. F. Ryley
Affiliation:
Imperial Chemical Industries Ltd., Pharmaceuticals Division, Alderley Park, Macclesfield, Cheshire
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Extract

Chick embryos have been infected with sporozoites of Eimeria tenella, but not with E. brunetti, and died from coccidiosis 5 days after infection.

Chick embryos can be protected from death due to coccidiosis by some but not all drugs which give a therapeutic response in chickens. The system is therefore not satisfactory as a screening tool, but may have applications in studies on the nature of drug activity.

Type
Research Article
Information
Parasitology , Volume 58 , Issue 1 , February 1968 , pp. 215 - 220
Copyright
Copyright © Cambridge University Press 1968

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References

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