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Gut rest strategy and trophic feeding in the acute phase of critical illness with acute gastrointestinal injury

  • Dong Zhang (a1), Hongxiang Li (a1), Yuting Li (a1) and Lai Qu (a1)


Critically ill patients frequently suffer from gastrointestinal dysfunction as the intestine is a vulnerable organ. In critically ill patients who require nutritional support, the current guidelines recommend the use of enteral nutrition within 24–48 h and advancing towards optimal nutritional goals over the next 48–72 h; however, this may be contraindicated in patients with acute gastrointestinal injury because overuse of the gut in the acute phase of critical illness may have an adverse effect on the prognosis. We propose that trophic feeding after 72 h, as a partial gut rest strategy, should be provided to critically ill patients during the acute phase of illness as an organ-protective strategy, especially for those with acute gastrointestinal injury.

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Corresponding author

*Corresponding author: Hongxiang Li, email


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