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Subjective Memory in Multiple Sclerosis is Associated with Initial-Trial Learning Performance

Published online by Cambridge University Press:  17 March 2011

Denise Krch ,
James F. Sumowski ,
John DeLuca  and
Nancy Chiaravalloti
Denise Krch*
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey – New Jersey Medical School, Newark, New Jersey
James F. Sumowski
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey – New Jersey Medical School, Newark, New Jersey
John DeLuca
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey – New Jersey Medical School, Newark, New Jersey Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey – New Jersey Medical School, Newark, New Jersey
Nancy Chiaravalloti
Affiliation:
Kessler Foundation Research Center, West Orange, New Jersey Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey – New Jersey Medical School, Newark, New Jersey
*
Correspondence and reprint requests to: Denise Krch, Neuropsychology and Neuroscience Laboratory, Kessler Foundation Research Center, 300 Executive Drive, Suite 70, West Orange, New Jersey 07052. E-mail: dkrch@kesslerfoundation.org
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Abstract

Subjective reports of memory functioning are often included as part of neuropsychological evaluations. However, information from subjective measures often conflicts with formal testing results. The current study explored the relationships among self-reported memory functioning and objective learning and memory measures. Sixty-four multiple sclerosis (MS) patients completed a self-report memory questionnaire (Memory Functioning Questionnaire, MFQ) and objective measures of learning and memory (California Verbal Learning Test-II, CVLT-II; Open-Trial Selective Reminding Test, OT-SRT; and Prose Memory, PM). Significant positive correlations were found between self-reported memory functioning and recall following initial exposure to material: OT-SRT Trial 1 (r = .42; p = .001); CVLT-II Trial 1 (r = .39; p = .002): PM Immediate Recall (r = .28; p = .028). Subjective memory was unrelated to recall performance on subsequent learning trials, aggregate learning scores, or delayed free recall. Results suggest that self-reported memory functioning in MS patients may be specifically related to single-trial learning. (JINS, 2011, 17, 557–561)

Keywords

Multiple sclerosisCognitionLearningMemorySubjective assessmentNeuropsychological tests
Type
Brief Communications
Information
Journal of the International Neuropsychological Society , Volume 17 , Issue 3 , May 2011 , pp. 557 - 561
Copyright
Copyright © The International Neuropsychological Society 2011

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