Skip to main content Accessibility help
×
×
Home

Moyamoya disease in a patient with schizophrenia

  • DAN I. LUBMAN (a1) (a2) (a3), CHRISTOS PANTELIS (a1) (a2), PATRICIA DESMOND (a4), TINA-MARIE PROFFITT (a1) (a2) and DENNIS VELAKOULIS (a1) (a2) (a3)...

Abstract

We present the case of a 23-year-old Vietnamese male with a 2-year history of a psychotic illness marked by prominent negative symptoms, fatuousness and disturbed behavior. Neuroimaging revealed a prominent vascular flow void affecting the middle and anterior cerebral arteries, with associated increased collateral supply to the frontal cortex, consistent with Moyamoya disease. Neurological examination was unremarkable; however, neuropsychological assessment revealed significant executive dysfunction, including stimulus-driven behavior. Whilst the diagnosis of schizophrenia and Moyamoya disease may be coincidental, an interaction between the 2 diseases may have led to some of the atypical features of this case, including prominent executive dysfunction and marked sensitivity to psychotropic medication. We discuss the nature of possible interactions between the 2 conditions. This case also highlights the importance of re-evaluating patients with atypical or treatment-resistant psychoses for cerebral pathology. (JINS, 2003, 9, 806–810.)

Copyright

Corresponding author

Reprint requests to: Dan Lubman, Cognitive Neuropsychiatry Research and Academic Unit, Sunshine Hospital, 176 Furlong Rd., St. Albans, Victoria 3021, Australia. E-mail: dan.lubman@mh.org.au
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Journal of the International Neuropsychological Society
  • ISSN: 1355-6177
  • EISSN: 1469-7661
  • URL: /core/journals/journal-of-the-international-neuropsychological-society
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Keywords

Type Description Title
PDF

 PDF (160 KB)
160 KB

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed