1.Du, ZY, Liu, YJ, Tian, LX, et al. (2015) Effect of dietary lipid level on growth, feed utilization and body composition by juvenile grass carp (Ctenopharyngodon idella). Aquac Nutr 11, 139–146.
2.Li, X, Jiang, Y, Liu, W, et al. (2012) Protein-sparing effect of dietary lipid in practical diets for blunt snout bream (Megalobrama amblycephala) fingerlings: effects on digestive and metabolic responses. Fish Physiol Biochem 38, 529–541.
3.Cao, XF, Dai, YJ, Liu, MY, et al. (2019) High-fat diet induces aberrant hepatic lipid secretion in blunt snout bream by activating endoplasmic reticulum stress-associated IRE1/XBP1 pathway. Biochim Biophys Acta 1864, 213–223.
4.Dai, YJ, Jiang, GZ, Yuan, XY, et al. (2018) High-fat-diet-induced inflammation depresses the appetite of blunt snout bream (Megalobrama amblycephala) through the transcriptional regulation of leptin/mammalian target of rapamycin. Br J Nutr 120, 1422–1431.
5.Dai, YJ, Cao, XF, Zhang, DD, et al. (2019) Chronic inflammation is a key to inducing liver injury in blunt snout bream (Megalobrama amblycephala) fed with high-fat diet. Dev Comp Immunol 97, 28–37.
6.He, AY, Ning, LJ, Chen, LQ, et al. (2015) Systemic adaptation of lipid metabolism in response to low- and high-fat diet in Nile tilapia (Oreochromis niloticus). Physiol Rep 3, e12485.
7.Jin, M, Pan, T, Cheng, X, et al. (2019) Effects of supplemental dietary l-carnitine and bile acids on growth performance, antioxidant and immune ability, histopathological changes and inflammatory response in juvenile black seabream (Acanthopagrus schlegelii) fed high-fat diet. Aquaculture 504, 199–209.
8.Nath, S, Matozzo, V, Bhandari, D, et al. (2019) Growth and liver histology of Channa punctatus exposed to a common biofertilizer. Nat Prod Res 33, 1591–1598.
9.Aloui, F, Charradi, K, Hichami, A, et al. (2016) Grape seed and skin extract reduces pancreas lipotoxicity, oxidative stress and inflammation in high fat diet fed rats. Biomed Pharmacother 84, 2020–2028.
10.Bonda, TA, Szynaka, B, Sokołowska, M, et al. (2016) Interleukin 6 modulates PPARα and PGC-1α and is involved in high-fat diet induced cardiac lipotoxicity in mouse. Int J Cardiol 219, 1–8.
11.Chen, F, Chen, D, Zhao, X, et al. (2017) Interleukin-6 deficiency facilitates myocardial dysfunction during high fat diet-induced obesity by promoting lipotoxicity and inflammation. Biochim Biophys Acta 1863, 3128.
12.Jabri, MA, Sakly, M, Marzouki, L, et al. (2017) Chamomile (Matricaria recutita L.) decoction extract inhibits intestinal glucose absorption and attenuates high fat diet-induced lipotoxicity and oxidative stress. Biomed Pharmacother 87, 153–159.
13.Mahmoudi, M, Charradi, K, Limam, F, et al. (2018) Grape seed and skin extract as an adjunct to xenical therapy reduces obesity, brain lipotoxicity and oxidative stress in high fat diet fed rats. Obes Res Clin Pract 12, Suppl. 2, 115–126.
14.Day, CP (2006) From fat to inflammation. Gastroenterology 130, 207–210.
15.Wang, X, Li, Y, Hou, C, et al. (2015) Physiological and molecular changes in large yellow croaker (Pseudosciaena crocea R.) with high-fat diet-induced fatty liver disease. Aquac Res 46, 272–282.
16.Jin, M, Lu, Y, Yuan, Y, et al. (2017) Regulation of growth, antioxidant capacity, fatty acid profiles, hematological characteristics and expression of lipid related genes by different dietary n-3 highly unsaturated fatty acids in juvenile black seabream (Acanthopagrus schlegelii). Aquaculture 471, 55–65.
17.Jin, M, Monroig, Ó, Lu, Y, et al. (2017) Dietary DHA/EPA ratio affected tissue fatty acid profiles, antioxidant capacity, hematological characteristics and expression of lipid-related genes but not growth in juvenile black seabream (Acanthopagrus schlegelii). PLOS ONE 12, e0176216.
18.Jin, M, Yuan, Y, Lu, Y, et al. (2017) Regulation of growth, tissue fatty acid composition, biochemical parameters and lipid related genes expression by different dietary lipid sources in juvenile black seabream, Acanthopagrus schlegelii. Aquaculture 479, 25–37.
19.Yan, J, Liao, K, Wang, T, et al. (2015) Dietary lipid levels influence lipid deposition in the liver of large yellow croaker (Larimichthys crocea) by regulating lipoprotein receptors, fatty acid uptake and triacylglycerol synthesis and catabolism at the transcriptional level. PLOS ONE 10, e0129937.
20.Schindler, M, Pendzialek, M, Grybel, KJ, et al. (2017) Adiponectin stimulates lipid metabolism via AMPK in rabbit blastocysts. Hum Reprod 32, 1382–1392.
21.Blusztajn, JK (1998) Choline, a vital amine science. Science 281, 794–795.
22.National Research Council (2011) Nutrient Requirements of Fish and Shrimp. Washington, DC: National Academies Press.
23.Li, J, Zhang, D, Xu, W, et al. (2014) Effects of dietary choline supplementation on growth performance and hepatic lipid transport in blunt snout bream (Megalobrama amblycephala) fed high-fat diets. Aquaculture 434, 340–347.
24.Li, JY, Li, XF, Xu, WN, et al. (2016) Effects of dietary choline supplementation on growth performance, lipid deposition and intestinal enzyme activities of blunt snout bream Megalobrama amblycephal fed high-lipid diet. Aquac Nutr 22, 181–190.
25.Luo, Z, Wei, CC, Ye, HM, et al. (2016) Effect of dietary choline levels on growth performance, lipid deposition and metabolism in juvenile yellow catfish Pelteobagrus fulvidraco. Comp Biochem Physiol B Biochem Mol Biol 202, 1–7.
26.Qin, DG, Dong, XH, Tan, BP, et al. (2017) Effects of dietary choline on growth performance, lipid deposition and hepatic lipid transport of grouper (Epinephelus coioides). Aquac Nutr 23, 453–459.
27.Koca, SS, Bahcecioglu, IH, Poyrazoglu, OK, et al. (2008) The treatment with antibody of TNF-α reduces the inflammation, necrosis and fibrosis in the non-alcoholic steatohepatitis induced by methionine- and choline-deficient diet. Inflammation 31, 91–98.
28.Wu, P, Jiang, WD, Jiang, J, et al. (2016) Dietary choline deficiency and excess induced intestinal inflammation and alteration of intestinal tight junction protein transcription potentially by modulating NF-κB, STAT and p38 MAPK signaling molecules in juvenile Jian carp. Fish Shellfish Immunol 58, 462–473.
29.Zhao, HF, Jiang, WD, Liu, Y, et al. (2016) Dietary choline regulates antibacterial activity, inflammatory response and barrier function in the gills of grass carp (Ctenopharyngodon idella). Fish Shellfish Immunol 52, 139–150.
30.Lee, EY, Park, HH, Kim, YT, et al. (2001). Cloning and sequence analysis of the interleukin-8 gene from flounder (Paralichthys olivaceous). Gene 274, 237–243.
31.Wei, H, Yin, L, Feng, S, et al. (2015) Dual-parallel inhibition of IL-10 and TGF-β1 controls LPS-induced inflammatory response via NF-κB signaling in grass carp monocytes/macrophages. Fish Shellfish Immunol 44, 445–452.
32.Wu, XT, Yang, Z, Ansari, AR, et al. (2018) Visfatin regulates the production of lipopolysaccharide-induced inflammatory cytokines through p38 signaling in murine macrophages. Microb Pathogenesis 117, 55–59.
33.Wyns, H, Plessers, E, De Backer, P, et al. (2015) In vivo porcine lipopolysaccharide inflammation models to study immunomodulation of drugs. Vet Immunol Immunopathol 166, 58–69.
34.Plessers, E, Wyns, H, Watteyn, A, et al. (2015) Characterization of an intravenous lipopolysaccharide inflammation model in calves with respect to the acute-phase response. Vet Immunol Immunopathol 163, 46–56.
35.Pamukcu, B, Lip, GYH & Shantsila, E (2011) The nuclear factor-κB pathway in atherosclerosis: a potential therapeutic target for atherothrombotic vascular disease. Thromb Res 128, 117–123.
36.Öberg, F, Haseeb, A, Ahnfelt, M, et al. (2009) Herbal melanin activates TLR4/NF-κB signaling pathway. Phytomedicine 16, 477–484.
37.AOAC (2006) Official Methods of Analysis, 18th ed. Arlington, VA: Association of Official Analytical Chemists.
38.Jiao, B, Huang, X, Chan, CB, et al. (2006) The co-existence of two growth hormone receptors in teleost fish and their differential signal transduction, tissue distribution and hormonal regulation of expression in seabream. J Mol Endocrinol 36, 23–40.
39.Xue, L, Yang, Q, Xue, L, et al. (2008) Molecular characterization of myostatin in black seabream, Acanthopagrus schlegelii. DNA Seq 19, 217–223.
40.Jothikumar, N, Cromeans, TL, Robertson, BH, et al. (2006) A broadly reactive one-step real-time RT-PCR assay for rapid and sensitive detection of hepatitis E virus. J Virol Methods 131, 65–71.
41.Livak, KJ & Schmittgen, TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2 method. Methods 25, 402–408.
42.Jiang, J, Yin, L, Li, JY, et al. (2017) Glutamate attenuates lipopolysaccharide-induced oxidative damage and mRNA expression changes of tight junction and defensin proteins, inflammatory and apoptosis response signaling molecules in the intestine of fish. Fish Shellfish Immunol 70, 473–484.
43.Kumar, R & Joy, KP (2019) Stress hormones modulate lipopolysaccharide stimulation of head kidney interleukin-6 production in the catfish Heteropneustes fossilis: in vivo and in vitro studies. Gen Comp Endocrinol 279, 109–113.
44.Halver, JE (2002) The vitamins. In Fish Nutrition, 3rd ed., pp. 61–140 [Halver, JE and Hardy, RW, editors]. San Diego, CA: Academic Press.
45.Mai, K, Xiao, L, Ai, Q, et al. (2009) Dietary choline requirement for juvenile cobia, Rachycentron canadum. Aquaculture 289, 124–128.
46.Jiang, GZ, Wang, M, Liu, WB, et al. (2013) Dietary choline requirement for juvenile blunt snout bream, Megalobrama amblycephala. Aquac Nutr 19, 499–505.
47.Wu, P, Feng, L, Kuang, SY, et al. (2011) Effect of dietary choline on growth, intestinal enzyme activities and relative expressions of target of rapamycin and eIF4E-binding protein 2 gene in muscle, hepatopancreas and intestine of juvenile Jian carp (Cyprinus carpio var. Jian). Aquaculture 317, 107–116.
48.Yamamoto, Y (1981) Determination of toxicity by biochemical method. In Fishes as Laboratory, chapter 4, pp. 568–574 [Egami, N, editor]. Tokyo: Soft Science.
49.Cheng, D & Kong, H (2011) The effect of Lycium barbarum polysaccharide on alcohol-induced oxidative stress in rats. Molecules 16, 2542–2550.
50.Takeuchi-Yorimoto, A, Noto, T, Yamada, A, et al. (2013) Persistent fibrosis in the liver of choline-deficient and iron-supplemented l-amino acid-defined diet-induced non-alcoholic steatohepatitis rat due to continuing oxidative stress after choline supplementation. Toxicol Appl Pharmacol 268, 264–277.
51.Zhou, F, Shao, J, Xu, R, et al. (2010) Quantitative l-lysine requirement of juvenile black seabream (Sparus macrocephalus). Aquac Nutr 16, 194–204.
52.Zhou, Q, Jin, M, Elmada, ZC, et al. (2015) Growth, immune response and resistance to Aeromonas hydrophila of juvenile yellow catfish, Pelteobagrus fulvidraco, fed diets with different arginine levels. Aquaculture 437, 84–91.
53.Chen, H, Zhang, L, Li, X, et al. (2013) Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes. J Steroid Biochem 138, 445–454.
54.Su, CC, Chang, CS, Chou, CH, et al. (2015) l-Carnitine ameliorates dyslipidemic and hepatic disorders induced by a high-fat diet via regulating lipid metabolism, self-antioxidant capacity, and inflammatory response. J Funct Foods 15, 497–508.
55.Wang, T, Yang, B, Ji, R, et al. (2017) Omega-3 polyunsaturated fatty acids alleviate hepatic steatosis-induced inflammation through Sirt1-mediated nuclear translocation of NF-κB p65 subunit in hepatocytes of large yellow croaker (Larimichthys crocea). Fish Shellfish Immunol 71, 76–82.
56.Aoyama, T, Peters, JM, Iritani, N, et al. (1998) Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα). J Biol Chem 273, 5678–5684.
57.Kerner, J & Hoppel, C (2000) Fatty acid import into mitochondria. Biochim Biophys Acta 1486, 1–17.
58.Yang, JH (2010) Perfluorooctanoic acid induces peroxisomal fatty acid oxidation and cytokine expression in the liver of male Japanese medaka (Oryzias latipes). Chemosphere 81, 548–552.
59.Ma, J, Shao, Q, Xu, Z, et al. (2013) Effect of dietary n-3 highly unsaturated fatty acids on growth, body composition and fatty acid profiles of juvenile black seabream, Acanthopagrus schlegelii (Bleeker). J World Aquac Soc 44, 311–325.
60.Cowey, CB & Walton, MJ (1989) Intermediary metabolism. Fish Nutr 2, 259–329.
61.Minghetti, M, Leaver, MJ & Tocher, DR (2011) Transcriptional control mechanisms of genes of lipid and fatty acid metabolism in the Atlantic salmon (Salmo salar L.) established cell line, SHK-1. Biochim Biophys Acta 1811, 194–202.
62.Takai, T, Saito, Y, Yamamoto, K, et al. (1988) Developmental changes of the content of acetyl-CoA carboxylase mRNA in chicken liver. Arch Biochem Biophys 266, 313–318.
63.Wakil, SJ (1961) Mechanism of fatty acid synthesis. J Lipid Res 2, 1–24.
64.Qian, Y, Li, XF, Zhang, DD, et al. (2015) Effects of dietary pantothenic acid on growth, intestinal function, anti-oxidative status and fatty acids synthesis of juvenile blunt snout bream Megalobrama amblycephala. PLOS ONE 10, e0119518.
65.Barbuio, R, Milanski, M, Bertolo, MB, et al. (2007) Infliximab reverses steatosis and improves insulin signal transduction in liver of rats feed a high fat diet. J Endocrinol 194, 539–550.
66.Chou, MC, Chang, R, Hung, YH, et al. (2013) Antrodia camphorata ameliorates high-fat-diet induced hepatic steatosis via improving lipid metabolism and antioxidative status. J Funct Foods 5, 1317–1325.
67.Varga, T, Czimmerer, Z & Nagy, L (2011) PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation. Biochim Biophys Acta 1812, 1007–1022.
68.Dong, YW, Jiang, WD, Liu, Y, et al. (2017) Threonine deficiency decreased intestinal immunity and aggravated inflammation associated with NF-κB and target of rapamycin signaling pathways in juvenile grass carp (Ctenopharyngodon idella) after infection with Aeromonas hydrophila. Br J Nutr 118, 92–108.
69.Zhang, A, Chen, D, Wei, H, et al. (2012) Functional characterization of TNF-α in grass carp head kidney leukocytes: induction and involvement in the regulation of NF-κB signaling. Fish Shellfish Immunol 33, 1123–1132.