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Well-differentiated liposarcoma arising in the parapharyngeal space: a case report and review of the literature

  • N Kikuchi (a1), T Nakashima (a2), J Fukushima (a3), K Nariyama (a4) and S Komune (a2)...



Liposarcomas rarely occur in the parapharyngeal space and only a few case reports exist. For curative therapy of liposarcoma, surgical excision remains the dominant modality. Although a wide surgical margin is important to prevent local recurrence, wide excision is often difficult in the head and neck region.

Case report:

We report a case of a 19-year-old female with a well-differentiated liposarcoma arising in the parapharyngeal space. We removed the tumour surgically utilising a cervical–parotid approach. The histological diagnosis was well-differentiated sclerosing liposarcoma. There is no recurrence after five years and nine months of follow up.


The patient's age and the tumour site made it difficult for us to make a quantitative diagnosis before the operation. Well-differentiated liposarcoma rarely develop distant metastasis, but often recur locally. The benefit of adjuvant radiotherapy for well-differentiated liposarcoma is still not clear and careful and long-term follow up is necessary.


Corresponding author

Address for correspondence: N Kikuchi, Department of Otorhinolaryngology, Yamaguchi Red Cross Hospital, Yahatababa 53–1, Yamaguchi-City, Yamaguchi 753–0092, Japan Fax:+81 83 925 1474 E-mail:


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