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Studying the result of underlay myringoplasty using platelet-rich plasma

  • S P S Yadav (a1), J S Malik (a1), P Malik (a1), P K Sehgal (a2), J S Gulia (a1) and R K Ranga (a1)...



Perforations of the tympanic membrane are treated with various surgical techniques and materials. This study aimed to determine the efficacy of platelet-rich plasma during underlay myringoplasty.


The study included 40 patients. Autologous platelet-rich plasma was applied in-between temporalis fascia graft and tympanic membrane remnant during underlay myringoplasty in group 1 (n = 20). The outcome was evaluated after three months and compared with group 2 (n = 20), a control group that underwent routine underlay tympanoplasty.


After three months’ follow up, graft uptake was 95 per cent in group 1 and 85 per cent in group 2 (p < 0.03). Mean hearing threshold gain was 18.62 dB in group 1 and 13.15 dB in group 2. This difference was statistically significant (p < 0.01).


Platelet-rich plasma, with its ease of preparation technique, availability, low cost, autologous nature and good graft uptake rate, justifies its use in tympanoplasty type I procedures.


Corresponding author

Author for correspondence: Dr Priya Malik, Room no. 211, Girls Hostel, PGIMS, Rohtak 124001, Haryana, India E-mail:


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Dr P Malik takes responsibility for the integrity of the content of the paper



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