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Chlorhexidine gluconate skin levels and organism decolonization: what we know and what we don’t know

Published online by Cambridge University Press:  08 August 2024

Saskia V. Popescu*
Affiliation:
Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, USA
Katherine E. Goodman
Affiliation:
Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, USA Institute for Healthcare Computing, University of Maryland, Baltimore, MD, USA
Anthony D. Harris
Affiliation:
Department of Epidemiology & Public Health, University of Maryland School of Medicine, Baltimore, MD, USA Institute for Healthcare Computing, University of Maryland, Baltimore, MD, USA
*
Corresponding author: Saskia V. Popescu; Email: spopescu@som.umaryland.edu

Abstract

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Type
Commentary
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

Huang, SS, Singh, R, McKinnell, JA, et al. Decolonization to reduce postdischarge infection risk among MRSA carriers. N Engl J Med 2019;380:638650.CrossRefGoogle ScholarPubMed
Patel, A, Parikh, P, Dunn, AN, et al. Effectiveness of daily chlorhexidine bathing for reducing gram-negative infections: a meta-analysis. Infection Control & Hospital Epidemiology 2019;40:392399.CrossRefGoogle ScholarPubMed
Rhee, Y., Simms, A, et al. Relationship between chlorhexidine gluconate concentration and microbial colonization of patients’ skin. Infect Control Hosp Epidemiol. Published online May 28, 2024. doi: 10.1017/ice.2024.81.Google Scholar
Warren, BG, Nelson, A, Warren, DK, et al. Impact of preoperative chlorhexidine gluconate (CHG) application methods on preoperative CHG skin concentration. Infect Control Hosp Epidemiol. 2021;42:464466.CrossRefGoogle ScholarPubMed
Musuuza, JS, Guru, PK, O’Horo, JC, et al. The impact of chlorhexidine bathing on hospital-acquired bloodstream infections: a systematic review and meta-analysis. BMC Infect Dis. 2019;19(1):416.CrossRefGoogle ScholarPubMed