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A particular P-element insertion is correlated to the P-induced hybrid dysgenesis repression in Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

Dominique Higuet ,
Dominique Anxolabéhére  and
Danielle Nouaud
Dominique Higuet*
Affiliation:
Mécanimes moléculaires de la spéciation, Université Pierre & Marie Cure, Tour 42 4éme et., 4 Place Jussieu, 75005 Paris, France
Dominique Anxolabéhére
Affiliation:
Mécanimes moléculaires de la spéciation, Université Pierre & Marie Cure, Tour 42 4éme et., 4 Place Jussieu, 75005 Paris, France
Danielle Nouaud
Affiliation:
Mécanimes moléculaires de la spéciation, Université Pierre & Marie Cure, Tour 42 4éme et., 4 Place Jussieu, 75005 Paris, France
*
* Corresponding author.

Summary

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Transposable P elements in Drosophila melanogaster cause hybrid dysgenesis if their mobility is not repressed. The ability to regulate the dysgenic activity of the P elements depends on several mechanisms, one of which hypothesized that a particular deleted P element (the KP element) results in a non-susceptibility which is biparentally transmitted. In this study totally nonsusceptible lines, and susceptible lines containing exclusively KP elements (IINS2 line and IIS2 line) were isolated from a M' strain. We show that non-susceptibility is correlated with a particular insertion of one KP element located at the cytological site 47D1. The repression ability of the GD sterility is determined by a recessive chromosomal factor, and cannot be due to the KP-element number. Here the repression of the P mobility is associated with reduction of the P transcripts and the inhibition of P promoter activity.

Type
Research Article
Information
Genetics Research , Volume 60 , Issue 1 , August 1992 , pp. 15 - 24
Copyright
Copyright © Cambridge University Press 1992

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