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Ziprasidone-induced priapism requiring surgical treatment

Presented in part at the 13th Congress of the Association of European Psychiatrists Munich, Germany, April 2–6, 2005

Published online by Cambridge University Press:  16 April 2020

Kenneth R. Kaufman ,
Lauren Stern ,
Arash Mohebati ,
Aviva Olsavsky  and
Jonathan Hwang
Kenneth R. Kaufman*
Affiliation:
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite #2200, New Brunswick, NJ 08901, USA Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite #2200, New Brunswick, NJ 08901, USA
Lauren Stern
Affiliation:
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite #2200, New Brunswick, NJ 08901, USA
Arash Mohebati
Affiliation:
Department of Surgery, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite #2200, New Brunswick, NJ 08901, USA
Aviva Olsavsky
Affiliation:
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite #2200, New Brunswick, NJ 08901, USA
Jonathan Hwang
Affiliation:
Department of Surgery, UMDNJ-Robert Wood Johnson Medical School, 125 Paterson Street, Suite #2200, New Brunswick, NJ 08901, USA
*
*Corresponding author. Tel.: +1 732 235 7647; fax: +1 732 235 7677. E-mail address:kaufmakr@umdnj.edu (K.R. Kaufman).
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Abstract

Both typical and atypical antipsychotic psychotropics have been reported to cause ischemic priapism presumptively secondary to alpha1-adrenergic blockade. This condition is a urologic emergency for if not evaluated and treated appropriately, long-term sequelae include erectile dysfunction and impotence. This paper addresses the first reported case of priapism requiring surgical intervention presumed to be secondary to ziprasidone. Increased clinician and patient education regarding priapism is required in order to minimize this adverse event and to maximize immediate treatment.

Keywords

ZiprasidonePriapismTreatmentShuntAtypical antipsychoticsErectile dysfunction
Type
Short communication
Information
European Psychiatry , Volume 21 , Issue 1 , January 2006 , pp. 48 - 50
Copyright
Copyright © Elsevier SAS 2006

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