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The synthetic cannabinoids: JWH, four years of analysis

Published online by Cambridge University Press:  23 March 2020

L. Galindo ,
M. Grifell ,
P. Quintana ,
A. Palma ,
J. Tirado ,
M. Ventura ,
I. Fornis ,
M. Torrens  and
M. Farré
L. Galindo*
Affiliation:
Institut de Neuropsiquiatria i Addiccions, Parc de Salut Mar, IMIM, Universitat Autònoma de Barcelona, Psychiatry, Barcelona, Spain
M. Grifell
Affiliation:
Institut de Neuropsiquiatria i Addiccions, Parc de Salut Mar, IMIM, Universitat Autònoma de Barcelona, Psychiatry, Barcelona, Spain
P. Quintana
Affiliation:
Energy Control, Asociación Bienestar y Desarrollo, Energy Control, Parc de Salut Mar, Medina de Familia, Barcelona, Spain
A. Palma
Affiliation:
Institut de Neuropsiquiatria i Addiccions, Parc de Salut Mar, IMIM, Universitat Autònoma de Barcelona, Psychiatry, Barcelona, Spain
J. Tirado
Affiliation:
IMIM, Adictions, Barcelona, Spain
M. Ventura
Affiliation:
Energy Control, Asociación Bienestar y Desarrollo, Energy Control, Barcelona, Spain
I. Fornis
Affiliation:
Energy Control, Asociación Bienestar y Desarrollo, Energy Control, Barcelona, Spain
M. Torrens
Affiliation:
Institut de Neuropsiquiatria i Addiccions, Parc de Salut Mar, IMIM, Universitat Autònoma de Barcelona-, Adictions, Barcelona, Spain
M. Farré
Affiliation:
Hospital Universitari Germans Trías i Pujol, IGTP, Universitat Autònoma de Barcelona, Pharmacology, Barcelona, Spain
*
* Corresponding author.

Abstract

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Introduction

Since 2004, herbal mixtures for smoking use have been sold under the generic brand “Spice”. Many of them contain synthetic cannabinoids (agonists of the cannabinoid receptors). JWH-018 was one of the first spice drugs. There is no scientific evidence of their effects on humans, except cases of intoxications and users opinions.

Objective

The present study describes the presence of the synthetic cannabinoids JWH's and their characteristics in the samples delivered for analysis to the harm reduction NGO Energy Control from 2010 to 2014 in Spain.

Methods

From 15,814 samples analyzed from 2010 to 2014, those containing synthetic cannabinoids JWH's were studied (n = 47). Analysis was done by gas chromatography–mass spectrometry.

Results

From these 47 samples containing JWH, 55% were delivered as “legal highs” (n = 21) and 44% as JWH. Most common presentations were powder 47% and herbals 32%. Samples containing JWH 45%(n = 21) were mixed with more than one kind of JWH or were adulterated and other active principles were found 28% (n = 13) JWH-018, 11% (n = 5) JWH-210, 8% (n = 4) JWH-081 and the 6% WH-250 (n = 3). Origin of the sample was Catalunya 23% (n = 11), other provinces of Spain 46% (n = 22); other EU countries 23% (n = 11) and internet-unknown country 8% (n = 8). From the (n = 47) samples, were delivered (n = 16) in 2012, (n = 12) in 2013, (n = 11) in 2011, (n = 3) in 2010 and (n = 3) in 2014.

Conclusion

JWH'S represent a low percentage of new psychoactive substances analyzed. Its presence in the market seems decreasing.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
EW05
Information
European Psychiatry , Volume 33 , Issue S1: Abstracts of the 24th European Congress of Psychiatry , March 2016 , pp. S115 - S116
Copyright
Copyright © European Psychiatric Association 2016
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