The given clinical-catamnethetic research was carried out on the basis of the department of the first psychotic epizode in « Specialized Clinical Psychiatric hospital №1» of the Department of Public Health Services of Krasnodar territory, Russia on the sample of 286 patients with the first psychotic symptoms who underwent treatment during 2006–2008 years. The medical-rehabilitation programme included psychopharmacological treatment and psychoeducational studies of both patients and their relatives, and a control group (100 individuals). Psychoeducational studies with relatives of the patients of the control group were not organized.

The research shows the evident effectiveness of psycho-education of relatives of the patients with first psychotic episode for better patients’ compliance.