It is known now that the dynamics and prognosis of stress-related disorders depends on the persistence of stress syndrome (re-experiencing, avoidance/overcoming, arousal) related to the symptoms of anxiety. Much less attention had paid to other ways of dynamics of stress-related disorders. The preliminary results of the investigation of stress-related disorders in general and specialized medical practice have shown three affective ways of psychic trauma fixation and stress-related disorders persistence – anxious, melancholic and apathetic. For further elaboration of affective model of stress-related disorders integrated psychiatric and psychological approach is applying.