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Prescribing practices in psychiatric hospitals in Eastern Europe

Published online by Cambridge University Press:  16 April 2020

V. Jordanova ,
N.P. Maric ,
V. Alikaj ,
M. Bajs ,
T. Cavic ,
D. Iosub ,
A. Mihai ,
A. Szalontay  and
N. Sartorius
V. Jordanova*
Affiliation:
Imperial College London, Charing Cross Hospital Campus, The Claybrook Centre, St. Dunstan's Road, LondonW6 8RP, United Kingdom
N.P. Maric
Affiliation:
Institute of Psychiatry, KSS and School of Medicine, University of Belgrade, Serbia
V. Alikaj
Affiliation:
University Hospital “Mother Teresa”, Tirana, Albania
M. Bajs
Affiliation:
Clinical Hospital Center Zagreb, Zagreb, Croatia
T. Cavic
Affiliation:
Institute for Neuropsychiatry “Dr Laza Lazarevic”, Belgrade, Serbia
D. Iosub
Affiliation:
Department of Psychiatry, Hospital Centre, 67170Brumath, France
A. Mihai
Affiliation:
University of Medicine and Pharmacy, Targu Mures, Romania
A. Szalontay
Affiliation:
University of Medicine and Pharmacy, Iasi, Romania
N. Sartorius
Affiliation:
University of Geneva, Geneva, Switzerland
*
⁎Corresponding author. E-mail address: vj22@le.ac.uk(V. Jordanova).
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Abstract

Background

There has been no evidence about the prescribing practices in psychiatric care in Eastern Europe.

Aims

To examine the patterns of psychotropic prescribing in five countries of Eastern Europe.

Method

We conducted a one-day census of psychiatric treatments used in eight psychiatric hospitals in Albania, Croatia, Macedonia, Serbia and Romania. We examined clinical records and medication charts of 1304 patients.

Results

The use of polypharmacy was frequent across all diagnostic groups. Only 6.8% of patients were on monotherapy. The mean number of prescribed drugs was 2.8 (SD 0.97) with 26.5% receiving two drugs, 42.1% receiving three drugs and 22.1% being prescribed four or more psychotropic drugs. Typical antipsychotics were prescribed to 63% and atypical antipsychotics to 40% of patients with psychosis. Older generations of antidepressants were prescribed to 29% of patients with depression. Anxiolitic drugs were prescribed to 20.4% and benzodiazepines to 68.5% of patients. One third of patients received an anticholinergic drug on a regular basis.

Conclusions

Older generation antipsychotics and antidepressants were used more frequently than in the countries of Western Europe. Psychotropic polypharmacy is a common practice. There is a need for adopting more evidence-based practice in psychiatric care in these countries.

Keywords

Psychotropic prescribingPatternsMonotherapyPolypharmacyEvidence-based practice
Type
Original article
Information
European Psychiatry , Volume 26 , Issue 7 , October 2011 , pp. 414 - 418
Copyright
Copyright © European Psychiatric Association 2010

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