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Physical health comorbidities in women with personality disorder: Data from the Geelong Osteoporosis Study

Published online by Cambridge University Press:  23 March 2020

SE Quirk ,
AL Stuart ,
SL Brennan-Olsen ,
JA Pasco ,
M Berk ,
AM Chanen ,
H Koivumaa-Honkanen ,
MA Kotowicz ,
PS Lukkala  and
LJ Williams
SE Quirk*
Affiliation:
Deakin University, IMPACT Strategic Research Centre, School of Medicine, Geelong, Australia
AL Stuart
Affiliation:
Deakin University, IMPACT Strategic Research Centre, School of Medicine, Geelong, Australia
SL Brennan-Olsen
Affiliation:
Deakin University, IMPACT Strategic Research Centre, School of Medicine, Geelong, Australia Institute of Health and Ageing, Australian Catholic University, Melbourne, Australia
JA Pasco
Affiliation:
Deakin University, IMPACT Strategic Research Centre, School of Medicine, Geelong, Australia Melbourne Medical School-Western Campus, Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Melbourne, Australia
M Berk
Affiliation:
Department of Psychiatry, University of Melbourne, Melbourne, Australia Orygen, the National Centre of Excellence in Youth Mental Health, Melbourne, Australia & Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia Barwon Health and the Geelong Clinic, Swanston Centre, Geelong, Australia Florey Institute for Neuroscience and Mental Health, Melbourne, Melbourne, Australia
AM Chanen
Affiliation:
Orygen, the National Centre of Excellence in Youth Mental Health, Melbourne, Australia & Centre for Youth Mental Health, The University of Melbourne, Melbourne, Australia
H Koivumaa-Honkanen
Affiliation:
Institute of Clinical Medicine, Psychiatry, University of Eastern Finland (UEF), Kuopio, Finland Departments of Psychiatry, Kuopio University Hospital, Kuopio; South-Savonia Hospital District, Mikkeli; North Karelia Central Hospital, Joensuu; SOSTERI, Savonlinna; SOTE, Iisalmi; Lapland Hospital District, Rovaniemi, Finland Clinic of Child Psychiatry, University Hospital of Oulu, Oulu, Finland
MA Kotowicz
Affiliation:
Melbourne Medical School-Western Campus, Faculty of Medicine, Dentistry & Health Sciences, University of Melbourne, Melbourne, Australia School of Medicine, Deakin University, Geelong, Australia
PS Lukkala
Affiliation:
School of Medicine, Faculty of Health Sciences, UEF, Kuopio, Finland Bone and Cartilage Research Unit, Surgery, Institute of Clinical Medicine, UEF, Kuopio, Finland
LJ Williams
Affiliation:
Deakin University, IMPACT Strategic Research Centre, School of Medicine, Geelong, Australia
*
*Corresponding author. Deakin University, IMPACT Strategic Research Centre, School of Medicine, Barwon Health, PO box 281, Ryrie Street, Geelong VIC 3220, Australia. Tel.: +61 405250358. E-mail address:shae.quirk@barwonhealth.org.au (S.E. Quirk).
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Abstract

Background

Associations between common psychiatric disorders, psychotic disorders and physical health comorbidities are frequently investigated. The complex relationship between personality disorders (PDs) and physical health is less understood, and findings to date are varied. This study aims to investigate associations between PDs with a number of prevalent physical health conditions.

Methods

This study examined data collected from women (n = 765; ≥ 25 years) participating in a population-based study located in south-eastern Australia. Lifetime history of psychiatric disorders was assessed using the semi-structured clinical interviews (SCID-I/NP and SCID-II). The presence of physical health conditions (lifetime) were identified via a combination of self-report, medical records, medication use and clinical data. Socioeconomic status, and information regarding medication use, lifestyle behaviors, and sociodemographic information was collected via questionnaires. Logistic regression models were used to investigate associations.

Results

After adjustment for sociodemographic variables (age, socioeconomic status) and health-related factors (body mass index, physical activity, smoking, psychotropic medication use), PDs were consistently associated with a range of physical health conditions. Novel associations were observed between Cluster A PDs and gastro-oesophageal reflux disease (GORD); Cluster B PDs with syncope and seizures, as well as arthritis; and Cluster C PDs with GORD and recurrent headaches.

Conclusions

PDs were associated with physical comorbidity. The current data contribute to a growing evidence base demonstrating associations between PDs and a number of physical health conditions independent of psychiatric comorbidity, sociodemographic and lifestyle factors. Longitudinal studies are now required to investigate causal pathways, as are studies determining pathological mechanisms.

Keywords

Personality disorderComorbidityPhysical health conditionsEpidemiologyMedical morbidity
Type
Original article
Information
European Psychiatry , Volume 34 , April 2016 , pp. 29 - 35
Copyright
Copyright © European Psychiatry 2016

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