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Pathopsychological assessment of pediatric patients with autoimmune diseases of central nervous system

Published online by Cambridge University Press:  13 August 2021

J. Fedorova ,
N. Burlakova ,
J. Mikadze  and
U. Azizova
J. Fedorova
Affiliation:
Department Of Neuro- And Pathopsychology, Lomonosov Moscow State University, Moscow, Russian Federation
N. Burlakova*
Affiliation:
Department Of Neuro- And Pathopsychology, Lomonosov Moscow State University, Moscow, Russian Federation
J. Mikadze
Affiliation:
Department Of Neuro- And Pathopsychology, Lomonosov Moscow State University, Moscow, Russian Federation
U. Azizova
Affiliation:
Department Number 1, Russian Children’s Clinical Hospital, Moscow, Russian Federation
*
*Corresponding author.

Abstract

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Introduction

Autoimmune diseases of central nervous system (CNS) are wide spread in children. In some cases, mental disturbances in such patients are barely noticeable in the beginning, which hinders early detection of risks in the child’s mental development.

Objectives

The study focuses on comparative analysis of the structure of mental disorders in pediatric patients with autoimmune diseases of CNS.

Methods

Research includes two cases: girls aged 14 and 16, one with acute disseminated encephalomyelitis (ADEM), disease onset at 4 years and 11 months, and another with multiple sclerosis (MS), disease onset at 5 years and 5 months. The following methods were used: analysis of patient’s medical record, interview with neurologists, pathopsychological assessment.

Results

Common features in both cases: 1) organic brain disorders; 2) patients do not demonstrate intellectual deterioration, can master regular school curriculum; 3) detected mental disturbances reflect risks for mental and personality development. Specific features: 1) the patient with MS demonstrates polymorphism of mental disorders, while the patient with ADEM — homogeneity of mental disorders; 2) main problems of the patient with MS are related to self-regulation, which makes the general picture similar to pseudo-frontal syndrome; the patient with ADEM has major neurodynamic disturbances, which has similarity to psychoorganic syndrome; 3) predictors of personality disorders detected in case of MS determine the negative prognosis for mental development.

Conclusions

The delineated features evidence for further psychological study of CNS autoimmune diseases and formulation of criteria for clinical psychological assessment. These patients need to be monitored by psychologists to prevent personality disorders.

Disclosure

No significant relationships.

Keywords

CNS diseaseautoimmune diseasepathopsychological assessment
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S630
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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