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P-177 - Hopelessness and Suicidality in Major Depressive Disorder in Patients With Cyclothymic Temperament

Published online by Cambridge University Press:  15 April 2020

A. Forte ,
M. Innamorati ,
Z. Rihmer ,
H. Akiskal ,
M. Amore ,
X. Gonda ,
G. Serafini ,
D. Erbuto ,
M. Pompili  and
P. Girardi
A. Forte
Affiliation:
Mental Health and Sensory Functions, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza Università di Roma, Rome, Italy
M. Innamorati
Affiliation:
Mental Health and Sensory Functions, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza Università di Roma, Rome, Italy
Z. Rihmer
Affiliation:
Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary
H. Akiskal
Affiliation:
International Mood Center, La Jolla, San Diego, CA, USA San Diego Veterans Administration Medical Center, San Diego, CA, USA
M. Amore
Affiliation:
Department of Neurosciences Division of Psychiatry, University of Parma, Parma, Italy
X. Gonda
Affiliation:
Department of Clinical and Theoretical Mental Health, Faculty of Medicine, Semmelweis University, Budapest, Hungary
G. Serafini
Affiliation:
Mental Health and Sensory Functions, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza Università di Roma, Rome, Italy
D. Erbuto
Affiliation:
Mental Health and Sensory Functions, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza Università di Roma, Rome, Italy
M. Pompili
Affiliation:
Mental Health and Sensory Functions, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza Università di Roma, Rome, Italy McLean Hospital, Harvard Medical School, Boston, MA, USA
P. Girardi
Affiliation:
Mental Health and Sensory Functions, Suicide Prevention Center, Sant’ Andrea Hospital, Sapienza Università di Roma, Rome, Italy

Abstract

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Background

The aim of the present study was to assess sociodemographic and clinical differences between BD patients, pure MDD patients, and MDD patients with cyclothymic temperament (MDD-CYC).

Methods

Participants were 281 adult inpatients (134 men and 147 women) consecutively admitted to the Department of Psychiatry of the Sant'Andrea University Hospital in Rome, Italy, between January 2008 and June 2010. The patients completed the Hamilton Scale for Depression (HAMD17), the Young Mania Rating Scale, the TEMPS-A (Temperament Evaluation of the Memphis, Pisa, Paris and San Diego - Autoquestionnaire) and the Beck Hopelessness Scale.

Results

38.7% of the MDD patients met criteria to be included in the MDD-CYC group. Above 93% of the MDD-CYC reported suicidal ideation (27.6% suicide attempts) at the item 3 of the HAMD17.Furthermore, MDD-CYC patients reported higher hopelessness compered to other patients.

Limitations

Our results are potentially limited by the small number of MDD-CYC patients included in the sample.

Conclusions

Our results support the clinical usefulness of the concept of soft bipolar spectrum. Patients with unipolar depression and cyclothymic temperament differ from pure MDD patients and BD patients in terms of temperamental profile and clinical variables.

Type
Abstract
Information
European Psychiatry , Volume 27 , Issue S1: Abstracts of the 20th European Congress of Psychiatry , 2012 , pp. 1
Copyright
Copyright © European Psychiatric Association 2012
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