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P01-365 Safety of second-generation antipsychotics in children-questionnaire evaluation in psychiatrists

Published online by Cambridge University Press:  16 April 2020

A. Wisniewski ,
A. Acewicz  and
K. Brewczyk
A. Wisniewski
Affiliation:
Department of Child and Adolescent Psychiatry, Medical University of Warsaw, Poland
A. Acewicz
Affiliation:
Zakład Farmakologii i Fizjologii Układu Nerwowego, Instytut Psychiatrii i Neurologii, Warszawa, Poland
K. Brewczyk
Affiliation:
Department of Child and Adolescent Psychiatry, Medical University of Warsaw, Poland

Abstract

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Atypical antipsychotics are more safe than first generation drugs. But some researchers suggest that children and adolescents might be more sensitive than adults to developing antipsychotic-related adverse side effects. The standards of safety monitoring strategies do not exist in Poland.

Objective

The aim of this study was to estimate physicians awareness to side effects in youth population treated with antipsychotics.

Material

20 questionnaires filled up by polish child psychiatrists.

Method

Information from author's questionnaire concerns side effects observed in antipsychotics medicated children, psychiatrists own preferences in safety monitoring strategies were analyzed.

Results

Atypical antipsychotics are used in 25% of medicated children. Risperidon is the most popular antipsychotic in psychotic and non-psychotic indications (81%, 66%), afterwards olanzapine (54%, 30%) and quetiapine (34%, 24%). The most common indications for antipsychotics in children are: tics (55%), conduct disorders (53%) and schizophrenia (45%). Before drug initiation doctors check liver enzymes (GOT, GTP) (98%), hematology (98%), glucose level (95%), weight and height (91%), ECG (90%). The most common side effects observed are: weigh gain (63%), somnolence (59%), prolactin elevation (47%), attention deficits (43%).

Conclusion

In spite of lack of safety monitoring standards in youth population psychiatrists seem to be aware and careful in atypical neurolpetic treatment in children.

Type
Research Article
Information
European Psychiatry , Volume 26 , Issue S2: Abstracts of the 19th European Congress of Psychiatry , March 2011 , pp. 367
Copyright
Copyright © European Psychiatric Association2011
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