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Neuropsychological function in subjects with psychotic and affective disorders. Relationship to diagnostic category and duration of illness

Published online by Cambridge University Press:  16 April 2020

H. Verdoux  and
F. Liraud
H. Verdoux
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux 2, Hôpital Charles Perrens, 121 rue de la Béchade,33076Bordeaux cedex, France
F. Liraud*
Affiliation:
Department of Psychiatry, University Victor Segalen Bordeaux 2, Hôpital Charles Perrens, 121 rue de la Béchade,33076Bordeaux cedex, France
*
*Correspondence and reprints: Hélène Verdoux, CH Charles Perrens, Centre Carreire, 121 rue de la Béchade, 33076 Bordeaux cedex, France
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Summary

Objective

To explore the links between neuropsychological performance, diagnostic category and duration of illness in subjects with psychotic and affective disorders.

Methods

Memory and executive abilities were tested in consecutively admitted patients with schizophrenia (N = 20), other non-schizophrenic psychotic disorders (N = 29), bipolar disorder (N = 33) and major depression (N = 19).

Results

Subjects with schizophrenia had poorer global memory performances than subjects with major depression, and poorer delayed verbal memory abilities than those from the other three diagnostic groups. Executive abilities explored by the Stroop test and the Wisconsin Card Sorting Test did not differ between diagnostic groups. Neuropsychological performances were not influenced by previous duration of illness.

Conclusions

Memory deficits are the most discriminatory cognitive features between subjects with schizophrenia and those with other psychotic or mood disorders. The fact that cognitive deficits are static whatever the diagnostic group indirectly suggests that they may have a neurodevelopmental origin in subjects with schizophrenia, but perhaps also in subjects with other psychotic and mood disorders.

Keywords

affective disorderduration of illnessneuropsychological performancepsychotic disorder
Type
Original article
Information
European Psychiatry , Volume 15 , Issue 4 , June 2000 , pp. 236 - 243
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS 2000

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